Anti-Sebum

Cleome Gynandra Leaf Extract

INCI: CLEOME GYNANDRA LEAF EXTRACT

Reviewed by Daisy · Last updated 2 Jun 2026

A plant extract traditionally used to help regulate sebum production and scalp health

Best For Skin Types

Oily, Combination

Addresses

Oil control, Sebum regulation

Usage Frequency

Daily

What Is Cleome Gynandra Leaf Extract?

Cleome gynandra leaf extract is derived from spider flower, a plant native to Africa and Asia with a long history of use in traditional medicine. The extract is obtained from the leaves of this plant and is used in skincare formulations primarily for its potential antiseborrhoeic properties—meaning it may help address excess sebum production and related scalp concerns.

In cosmetic products, this ingredient is typically incorporated into formulations targeting oily or combination skin types, though research into its specific mechanisms and efficacy in modern skincare remains limited.

How It Works

The exact mechanisms by which Cleome gynandra leaf extract influences sebum production are not fully characterised in peer-reviewed literature. However, the plant is thought to contain compounds that may interact with sebaceous gland activity or the skin's natural oil balance, though the specifics remain under-researched in modern dermatology.

Traditional use suggests antiseborrhoeic activity, but translating this into mechanistic understanding requires further clinical study.

Clinical Evidence & References

Published clinical research specifically examining Cleome gynandra leaf extract in skincare formulations is limited. The ingredient's reputation rests largely on traditional use and in vitro studies, rather than robust human clinical trials demonstrating efficacy at typical cosmetic concentrations.

Those interested in using products containing this extract should be aware that evidence for its effectiveness remains preliminary, and results may vary between individuals. Further research would help clarify its true benefit in modern skincare.

How to Use

This ingredient is typically found in shampoos, scalp treatments, and facial products formulated for oily or combination skin. Use as directed on the product label. If combining with other actives—particularly those addressing oil control or scalp health—monitor skin response, as cumulative effects are not well documented.

Safety & Precautions

Cleome gynandra leaf extract is generally considered safe for topical use and is well-tolerated by most skin types. No significant adverse effects have been widely reported, though patch testing is advisable for those with sensitive skin.

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