Peptides

Copper Tripeptide-1 Palmitamide

INCI: COPPER TRIPEPTIDE-1 PALMITAMIDE

Reviewed by Kate · Last updated 14 Aug 2026

Also known as: Copper Tripeptide-1 Palmitamide

A copper-binding peptide complex with antioxidant and skin-conditioning properties

Best For Skin Types

All, Mature, Dry

Addresses

Antioxidant protection, Fine lines, Elasticity, Skin conditioning

Usage Frequency

Daily

What Is Copper Tripeptide-1 Palmitamide?

Copper Tripeptide-1 Palmitamide is a synthetic peptide compound that combines three amino acids with a copper ion and a fatty acid chain (palmitate). Peptides are short chains of amino acids that can penetrate the outer layers of skin, and the addition of copper and the palmitate moiety is intended to enhance stability and skin affinity.

In skincare formulations, this ingredient functions as an antioxidant, helping to neutralise free radicals that can damage skin cells. It also has skin-conditioning properties, meaning it can improve the feel and appearance of skin texture.

Benefits for Your Skin

How It Works

The copper ion in this complex is believed to function as a cofactor for enzymes involved in skin renewal and collagen cross-linking, whilst the peptide portion may enhance penetration and the antioxidant effect. The palmitate fatty acid chain helps anchor the ingredient into the skin barrier, potentially improving retention.

As an antioxidant, the copper component can donate electrons to neutralise unpaired electrons in free radicals, preventing them from causing oxidative damage to skin cells and lipids.

Clinical Evidence & References

Research on copper peptide complexes suggests they have antioxidant activity and may support skin health, though the specific clinical evidence for this exact derivative is limited in peer-reviewed literature. Some studies indicate that copper peptides can support collagen production and skin firmness when used over several weeks, though results vary depending on formulation and concentration.

More robust clinical data would strengthen claims around this specific ingredient. As with many cosmetic peptides, real-world efficacy depends heavily on formulation stability, pH, and penetration ability.

How to Use

This ingredient is typically found in serums, moisturisers, and treatment products. Use as directed by the product instructions, generally once or twice daily. It works well alongside other antioxidants such as vitamin C or niacinamide, and is compatible with most skincare routines. Allow products to dry fully before layering other treatments.

Safety & Precautions

Generally well-tolerated by most skin types. As with all peptides, those with copper sensitivity should avoid. Patch test if you have very sensitive or reactive skin.

Frequently Asked Questions

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