Drometrizole Trisiloxane
INCI: Mexoryl XL
Reviewed by Kate · Last updated 18 Aug 2026
Also known as: Mexoryl XL
Known more commonly as Mexoryl XL Photostable UVA and UVB filter
EWG Safety Score
Drometrizole Trisiloxane products at Skintique
View all →What Is Drometrizole Trisiloxane?
Drometrizole trisiloxane, known also by its trade name Mexoryl XL, is a photostable UVA and UVB filter developed and patented by cosmetics company L’Oreal. Since its UVA protection peaks at 340 nanometers, it’s generally best to see this combined with other UV filters whose protection peaks further along the UVA range, which goes up to 400 nanometers.
Research has found that allergic reactions to drometrizole trisiloxane are considered rare; this UV filter is used in sun protection products sold in the EU, Canada, Australia, and Japan.
It is not currently in wide use in the United States because the U.S. Food and Drug Administration says there is not significant evidence yet showing it to be generally recognized as safe and effective for over-the-counter sunscreen use. Interestingly, the FDA has allowed L’Oreal to market a sunscreen in the U.S. that contains this filter.
Benefits for Your Skin
Clinical Evidence & References
- PubChem, Accessed April 2023, Website
- TrAC Trends in Analytical Chemistry, December 2022, ePublication
- Indian Journal of Dermatology, January-February 2020, pages 5-10
- Journal of the European Academy of Dermatology and Venereology, September 2008, pages 1,110-1,119
- Plastic and Reconstructive Surgery, September 2007, pages 1,071-1,075
- Photodermatology, Photoimmunology & Photomedicine, October 2004, pages 243-247
Published Research
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Mexoryl XL: Photostable UVA/UVB protection Photochem Photobiol Sci, 2017
From the Clinic
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Diethylhexyl Butamido Triazone
Synthetic, oil-soluble UV filter
Diethylhexyl Syringylidenemalonate
An ester that functions as an antioxidant and photostabiliser | Stabilises UV filters, especially avobenzone
Disodium Phenyl Dibenzimidazole Tetrasulfonate
A water-soluble chemical UV filter used in modern sunscreen formulations
Ecamsule
Photostable UVA filter Technical name is terephthalylidene dicamphor sulfonic acid
Ethyl Methoxycinnamate
A cinnamate-derived UV filter with potential melanin-regulating properties
Ethylhexyl Dimethyl Paba
A chemical UV filter that absorbs ultraviolet radiation to help protect skin from sun damage
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