Ethylbisiminomethylguaiacol Manganese Chloride
Reviewed by Daisy · Last updated 18 Aug 2026
Also known as: SpecKare® D-EUK-134, EUK-134, Superoxide Dismutase
Lab-synthesized antioxidant | Said to mimic superoxide dismutase and catalase
Addresses
EWG Safety Score
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What Is Ethylbisiminomethylguaiacol Manganese Chloride?
Ethylbisiminomethylguaiacol manganese chloride is a lab synthesized antioxidant also known by the trade names SpecKare® D-EUK-134 and EUK-134. According to its manufacturer, ethylbisiminomethylguaiacol manganese chloride mimics the free radical scavenging ability of superoxide dismutase (an enzyme found in the cells of living organisms) and catalase, another enzyme with potent antioxidant properties. Currently, there’s not a wealth of independent research on EUK-134’s benefits for skin, theoretically it’s a good ingredient to include in anti-aging formulations. Suggested usage levels of ethylbisiminomethylguaiacol manganese chloride are in the 0.1% range, speaking to its potential potency.
Benefits for Your Skin
Clinical Evidence & References
Published Research
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UL Prospector, Website, Accessed October 2025 [https://www.ulprospector.com/en/na/PersonalCare/Detail/5738/8574370/SpecKare-D-EUK-134-Ethylbisiminomethylguaiacol-Manganese-Chloride]
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CoSmile Europe, Website, Accessed October 2025 [https://cosmileeurope.eu/inci/detail/5429/ethylbisiminomethylguaiacol-manganese-chloride]
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SpecialChem, Website, Accessed October 2025 [https://www.specialchem.com/cosmetics/inci-ingredients/ethylbisiminomethylguaiacol-manganese-chloride]
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PubChem, Website, Accessed October 2025 [https://pubchem.ncbi.nlm.nih.gov/compound/Ethylbisiminomethylguaiacol-manganese-chloride]
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FDA.gov, Website, Accessed October 2025 [https://precision.fda.gov/ginas/app/ui/substances/SM5YJ88LTU]
Frequently Asked Questions
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