Fibroin
INCI: FIBROIN
Reviewed by Daisy · Last updated 14 Aug 2026
A silk-derived protein with potential for supporting skin repair and hydration
Best For Skin Types
All, Sensitive, Dry
Addresses
Usage Frequency
Daily
What Is Fibroin?
Fibroin is a naturally occurring protein extracted from silk fibres, typically sourced from silkworm cocoons. In skincare formulations, it serves primarily as a bulking agent that helps create structure and texture in products whilst offering film-forming properties on the skin's surface.
The protein is biocompatible and biodegradable, meaning it integrates well with skin tissue and breaks down naturally over time. This makes it a popular choice in both conventional skincare and advanced skin repair applications.
How It Works
Fibroin works through multiple mechanisms. As a film-former, it creates a permeable layer across the skin that helps reduce transepidermal water loss without occluding pores. The protein's structure allows it to interact gently with the skin barrier rather than sitting passively on the surface.
In more advanced formulations—such as hydrogels or wound-care products—fibroin can be engineered to release bioactive compounds gradually and support the skin's natural repair processes. The protein's biocompatibility means it integrates with skin tissue with minimal disruption.
Clinical Evidence & References
Research on fibroin in wound healing and tissue engineering contexts is promising. Studies indicate that silk fibroin-based materials can accelerate skin repair, reduce inflammation, and promote new blood vessel formation—properties that may support skin barrier health and recovery from damage.
However, most research has focused on specialist medical applications (wound dressings, tissue scaffolds) rather than cosmetic skincare formulations at typical concentrations. Evidence for fibroin's benefits in everyday skincare products remains limited, though its general biocompatibility and film-forming properties are well-established.
How to Use
Fibroin is typically present in products formulated to maximise its texture and film-forming benefits, such as serums, hydrogels, and masks. Apply to clean, dry or damp skin as part of your regular routine. It works well layered with other hydrating ingredients but is not essential for effective skincare.
Safety & Precautions
Frequently Asked Questions
From the Clinic
Not sure what your skin actually needs?
Two minutes, a few questions, and we’ll point you at what matters — no guesswork.
Take the skin quizRelated Ingredients
Ethylene …
A synthetic polymer that stabilises product texture and consistency
Ethyltrimonium Chloride Methacrylate/Hydrolyzed Wheat Protein Copolymer
A film-forming polymer that strengthens the skin barrier and improves texture
Euglena Gracilis Polysaccharide
A polysaccharide from microalgae that conditions skin and modulates texture
Gellan Gum
Texture enhancer
Glycereth-26
Synthetic, glycerin-based ingredient
Glyceryl Polymethacrylate
Blend of glycerin and polymethacrylic acid
Learn More About Skincare Ingredients
Explore our comprehensive ingredient glossary to understand what's in your products.
Browse All IngredientsShop Our Products
Find professional skincare solutions at Skintique.