Ginkgo Biflavones

Ginkgo biflavones are dimeric flavonoid compounds extracted from the leaves of Ginkgo biloba, one of the oldest living tree species. These polyphenolic molecules are prized in skincare for their antioxidant properties and their ability to influence blood flow and cellular signalling pathways in the skin.In formulations, ginkgo biflavones function primarily as skin protectants and antioxidants, helping to neutralise free radical damage and support the skin's natural defence mechanisms.

Ginkgo biflavones work through multiple mechanisms. They inhibit phosphodiesterase enzymes, which are involved in regulating cellular messenger molecules like cAMP and cGMP. By modulating these pathways, biflavones may enhance blood vessel relaxation and improve microcirculation to the skin.Additionally, their polyphenolic structure allows them to scavenge free radicals—reactive oxygen species that damage cell membranes and DNA. This antioxidant capacity helps protect skin cells from photoageing and environmental stress.

Ginkgo biflavones are typically found in serums, essences, and moisturisers. They work well alongside other antioxidants such as vitamin E or niacinamide. For best results, use as part of a consistent routine and combine with daily broad-spectrum sunscreen, since antioxidants complement rather than replace UV protection.

Ginkgo biloba extract is generally well-tolerated in topical skincare. Those with known sensitivities to ginkgo should avoid products containing this ingredient.