Peptides

Glycine Max Polypeptide

INCI: GLYCINE MAX POLYPEPTIDE

Reviewed by Kate · Last updated 2 Jun 2026

Also known as: Glycine Max Polypeptide

A soybean-derived peptide with preliminary research supporting skin barrier and inflammatory responses

Best For Skin Types

All, Sensitive

Addresses

Sensitivity, Redness, Barrier repair, Inflammation

Usage Frequency

Daily

What Is Glycine Max Polypeptide?

Glycine Max Polypeptide is a peptide derived from soybean (Glycine max). Peptides are short chains of amino acids, and those sourced from soy have been studied in traditional medicine and contemporary skincare research for their potential effects on skin health.

In formulations, it functions as a skin conditioning agent, working to support the skin's surface properties and overall condition.

How It Works

Research on soybean-derived extracts suggests they may work through multiple pathways. Studies indicate potential effects on JAK/STAT signalling and immune regulation, which are molecular processes involved in inflammatory skin conditions. The peptide may also support the production of filaggrin, a key protein in skin barrier function.

However, most available research examines whole soybean extracts or fermented forms rather than isolated polypeptides, so the precise mechanism of this specific ingredient remains somewhat unclear.

Clinical Evidence & References

Research on soybean derivatives shows promising results in controlled studies, particularly for inflammatory skin conditions including atopic dermatitis-like responses in animal models. Studies have documented reductions in inflammatory markers and improvements in skin barrier integrity when soybean extracts were administered.

It is important to note that most evidence comes from animal studies or laboratory work, and human clinical trials specifically investigating Glycine Max Polypeptide in skincare formulations are limited. The concentration at which this ingredient appears in cosmetic products (typically under 0.5%) may differ from concentrations used in research studies, so direct translation to skincare efficacy is uncertain.

How to Use

Glycine Max Polypeptide is typically found in serums, essences and moisturisers. Use as directed in your chosen formulation, usually once or twice daily. It can generally be layered with other skincare ingredients without concern, though introducing any new product gradually allows you to monitor your skin's response.

Safety & Precautions

Generally well-tolerated in cosmetic formulations. Those with soy sensitivity or allergy should check ingredient lists carefully, though topical exposure carries lower risk than ingestion.

Frequently Asked Questions

From the Clinic

Not sure what your skin actually needs?

Two minutes, a few questions, and we’ll point you at what matters — no guesswork.

Take the skin quiz

Learn More About Skincare Ingredients

Explore our comprehensive ingredient glossary to understand what's in your products.

Browse All Ingredients

Authorised Stockist

Official UK retailer

Tracked Delivery

Free UK shipping over £50

5 Star Rating

Trusted by thousands

Expert Advice

Free consultations