Horseradish Peroxidase

Horseradish peroxidase (HRP) is an enzyme derived from horseradish plants. In skincare, it functions as a skin conditioning agent with catalytic properties that enable specific biochemical reactions on the skin's surface.The enzyme works by catalysing oxidation reactions, which has led to its exploration in wound healing formulations and diagnostic applications. However, its use in mainstream skincare remains limited, and most research to date has focused on specialist medical or research applications rather than cosmetic benefit.

Horseradish peroxidase catalyses oxidation reactions involving hydrogen peroxide. When applied to skin, it accelerates the breakdown and conversion of certain molecules, which can be leveraged in wound healing formulations or diagnostic tools.In research contexts, HRP has been combined with plant extracts and hydrogels to enhance photothermal properties and antibacterial activity. The enzyme's mechanism is well-established in laboratory settings, though its practical benefit in routine skincare products remains under investigation.

If using a product containing horseradish peroxidase, follow the manufacturer's instructions for application frequency and quantity. As this ingredient is uncommon in mainstream skincare, always patch test first, particularly if you have sensitive skin or are using other active ingredients concurrently. Store products as directed to maintain enzyme stability.

Horseradish peroxidase is generally considered safe for topical use and is recognised in cosmetic applications. However, given its limited use in consumer skincare, comprehensive safety data is less extensive than for more established ingredients.