Houttuynia Cordata Extract
INCI: HOUTTUYNIA CORDATA EXTRACT
Reviewed by Kate · Last updated 14 Aug 2026
A plant extract traditionally used to support skin barrier function and reduce inflammatory responses
Best For Skin Types
All, Sensitive, Combination
Addresses
Effective Concentrations
1-5%
Usage Frequency
Daily
What Is Houttuynia Cordata Extract?
Houttuynia cordata extract is derived from a perennial plant native to East Asia, where it has been used in traditional medicine for centuries. The extract contains polyphenolic compounds, including quercitrin and hyperoside, which are responsible for many of its biological properties. In skincare formulations, it functions primarily as a skin conditioning agent.
The extract works by interacting with the skin's immune and barrier systems. Research suggests it may help modulate inflammatory pathways and support the skin's natural protective mechanisms, making it relevant for formulations targeting compromised or reactive skin states.
Benefits for Your Skin
How It Works
Houttuynia cordata extract appears to exert its effects primarily through modulation of cellular signalling pathways, particularly the mitogen-activated protein kinase (MAPK) pathway. This pathway is central to how skin cells respond to stress, inflammation, and environmental damage. By regulating these pathways, the extract may help reduce the production of inflammatory mediators and protect cells from apoptosis (cell death).
The polyphenolic compounds in the extract also possess antioxidant properties, which may help neutralise free radicals generated by UV exposure and other environmental stressors. This dual action—reducing inflammatory signalling whilst providing antioxidant support—suggests a multi-targeted approach to supporting skin resilience.
Clinical Evidence & References
Research in animal models and cell cultures shows that Houttuynia cordata polysaccharides can reduce markers of atopic dermatitis, including epidermal thickness, mast cell infiltration, and inflammatory cytokines. Studies also demonstrate that specific fractions of the extract (particularly those rich in quercitrin and hyperoside) protect human keratinocytes against UV-induced cell death and suppress inflammatory mediators such as IL-6, IL-8, and COX-2.
Additionally, preliminary evidence suggests the extract may modulate Th2 immune responses, which are relevant to allergic and inflammatory skin conditions. However, most available research has been conducted in cell cultures and animal models; human clinical trials are limited. Further investigation in human volunteers would help establish the clinical significance of these findings and optimal usage parameters.
Published Research
How to Use
Houttuynia cordata extract is typically found in serums, toners, and moisturisers at concentrations of 1% to 5%. As with any new ingredient, introduce it gradually into your routine to monitor tolerance. It can be layered with other actives, though combining it with high concentrations of vitamin C or acids may warrant cautious introduction given the cumulative inflammatory-modulating effects.
Safety & Precautions
Frequently Asked Questions
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Houttuynia Cordata Extract is a variant of Houttuynia Cordata Water, the form you will most often see on an ingredients list.
A plant water extract with antioxidant and purifying properties for balanced skincare
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