Peptides

Hydroxydecyl Ubiquinoyl Dipalmitoyl Glycerate

INCI: HYDROXYDECYL UBIQUINOYL DIPALMITOYL GLYCERATE

Reviewed by Kate · Last updated 14 Aug 2026

A stabilised coenzyme Q10 derivative designed to support skin conditioning and resilience

Best For Skin Types

All, Dry, Mature, Sensitive

Addresses

Dryness, Barrier repair, Fine lines

Usage Frequency

Daily

What Is Hydroxydecyl Ubiquinoyl Dipalmitoyl Glycerate?

Hydroxydecyl ubiquinoyl dipalmitoyl glycerate is a modified form of coenzyme Q10 (ubiquinone), a naturally occurring compound found in human cells. This version has been chemically altered to improve stability and penetration in skincare formulations, making it more suitable for topical use than standard CoQ10.

In skincare, it functions primarily as a skin conditioning agent, working to support the skin's natural protective mechanisms and help maintain a healthy skin surface.

How It Works

Coenzyme Q10 is involved in cellular energy production (ATP synthesis) within mitochondria. When applied topically, this stabilised derivative is thought to support cellular function and help protect skin cells from oxidative damage caused by environmental stressors such as UV exposure and pollution.

The chemical modifications made to this ingredient enhance its ability to remain stable in formulations and potentially penetrate the skin more effectively than unmodified CoQ10.

Clinical Evidence & References

Research on coenzyme Q10 in skincare has shown promising results for antioxidant protection and skin firmness, though most published evidence focuses on unmodified CoQ10 rather than this specific derivative. The modified form is designed to improve upon these properties through better stability and skin penetration.

Human clinical studies specific to this ingredient are limited. It is generally regarded as a safe and well-tolerated skin conditioning agent based on its use in cosmetic formulations and the established safety profile of CoQ10.

How to Use

This ingredient is typically found in serums, moisturisers and treatment products. Use as directed on the product packaging. It integrates well into most skincare routines and can be layered with other actives, though it is advisable to introduce any new product gradually if you have sensitive skin.

Safety & Precautions

Generally well-tolerated and suitable for most skin types. No significant cautions are noted; however, discontinue use if irritation occurs.

Frequently Asked Questions

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