Hydroxypalmitoyl Sphinganine

Hydroxypalmitoyl sphinganine is a ceramide—a type of lipid naturally present in skin. Also known as dihydroceramide, it's composed of a fatty acid (palmitic acid) bonded to a sphinganine base. This ingredient can be derived from natural sources or synthesised in laboratories, and functions as both a skin and hair conditioning agent.Ceramides are structural components of the skin's outer layer, where they sit between skin cells and help form the protective barrier that prevents water loss and shields against environmental irritants. When this barrier is compromised, skin tends to become dry,…

Hydrating. Helps with Barrier Repair

The skin barrier is composed of cells held together by lipids, including ceramides. When ceramides are depleted—through age, harsh cleansing, or environmental damage—the barrier weakens. This allows moisture to escape and irritants to penetrate more easily.When applied topically, hydroxypalmitoyl sphinganine integrates into this lipid matrix, filling gaps and reinforcing the barrier's structural integrity. This helps restore the skin's ability to retain water and function as an effective shield.

Hydroxypalmitoyl sphinganine is most effective when used as part of a consistent routine, typically in moisturisers or barrier-repair serums. For optimal results, apply to clean, slightly damp skin to help lock in hydration. It works well alongside other barrier-supporting ingredients and can be used both morning and evening.

Hydroxypalmitoyl sphinganine is well-tolerated by most skin types and is not known to cause irritation. It is suitable for sensitive skin and those with compromised barriers.