Ilex Aquifolium Leaf Extract
INCI: ILEX AQUIFOLIUM LEAF EXTRACT
Reviewed by Emma · Last updated 14 Aug 2026
A plant extract with antioxidant properties traditionally used to support skin conditioning
Best For Skin Types
All
Addresses
Usage Frequency
Daily
What Is Ilex Aquifolium Leaf Extract?
Ilex aquifolium leaf extract is derived from the leaves of the common holly plant, a species native to Western Europe. The extract contains naturally occurring phenolic compounds, including chlorogenic acid, rosmarinic acid, hesperidin, and quercetin, which contribute to its chemical profile.
In skincare formulations, this ingredient functions primarily as a skin conditioning agent. The phenolic compounds present in the extract have demonstrated antioxidant properties in laboratory studies, which may help protect skin from oxidative stress.
How It Works
The extract's primary mechanism appears to stem from its phenolic compounds, which function as antioxidants. These molecules can donate electrons to free radicals, stabilising them and preventing further oxidative damage to skin cells.
Laboratory studies have also indicated that certain compounds within the extract may inhibit tyrosinase activity, the enzyme responsible for melanin synthesis. However, whether this translates to meaningful effects on human skin requires further investigation.
Clinical Evidence & References
Research on Ilex aquifolium leaf extract is limited in the context of human skincare. In vitro studies have demonstrated notable antioxidant capacity and enzyme inhibitory properties, particularly against tyrosinase. These findings suggest potential utility in formulations designed to address oxidative stress and pigmentation concerns.
However, human clinical trials evaluating efficacy and safety in topical skincare applications are sparse. While the antioxidant profile is promising, claims regarding visible skin benefits should be considered preliminary until supported by human study data.
How to Use
This ingredient is typically used as part of a broader skincare formulation rather than as a standalone treatment. Apply products containing this extract as directed, usually once or twice daily. It pairs well with other antioxidants and stabilising ingredients in serums, moisturisers, and targeted treatments.
Safety & Precautions
Frequently Asked Questions
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Take the skin quizOther forms of Ilex Aquifolium Leaf Extract
These appear on ingredients lists under different names but are the same substance. Ilex Aquifolium Leaf Extract is the common form.
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