Isoniacinamide

Isoniacinamide is a structural isomer of niacinamide (vitamin B3), meaning it shares the same molecular formula but with a different atomic arrangement. Like niacinamide, it is a water-soluble B vitamin derivative used primarily as a skin conditioning agent in cosmetic formulations.This ingredient functions to support the skin's natural moisturisation and barrier maintenance processes, though it is less widely studied than its niacinamide counterpart.

As a niacinamide isomer, isoniacinamide is believed to work through similar pathways to niacinamide, supporting the skin's natural ceramide and lipid synthesis. This helps reinforce the stratum corneum—the outermost layer responsible for water retention and protection against external stressors.

Isoniacinamide is typically incorporated into serums, moisturisers and targeted treatments. It is generally stable in formulations and can be used daily as part of a regular skincare routine. No special application technique is required; follow the product instructions provided by the manufacturer.

Isoniacinamide is considered safe for topical use and is well-tolerated across most skin types. Those with known sensitivity to niacinamide or B vitamins should introduce products containing this ingredient cautiously.