Skin Conditioning

Lysozyme

INCI: LYSOZYME

Reviewed by Rosie · Last updated 14 Aug 2026

A naturally occurring protein with skin conditioning properties

Best For Skin Types

All, Sensitive

Addresses

Sensitivity, Barrier repair

Usage Frequency

Daily

What Is Lysozyme?

Lysozyme is an antimicrobial enzyme found naturally in many biological fluids, including tears, saliva, and egg white. In skincare, it is used as a skin conditioning agent derived from these natural sources.

The ingredient functions by helping to maintain skin's protective barrier and supporting its natural defence mechanisms, though its primary role in cosmetic formulations is to improve skin feel and condition rather than to deliver dramatic therapeutic effects.

How It Works

Lysozyme is a naturally antimicrobial protein that works by breaking down certain cell wall components in bacteria. In skincare, this property is thought to help support skin's natural defences, though the extent of this benefit in topical application remains modest compared to other antimicrobial approaches.

Beyond its antimicrobial action, lysozyme functions as a skin conditioning agent, helping to improve skin hydration and texture through its humectant and film-forming properties.

Clinical Evidence & References

Research on lysozyme in topical skincare is limited. Most evidence comes from studies examining its antimicrobial properties in laboratory settings or its use in oral and systemic medicine, rather than its cosmetic benefits when applied to skin.

While lysozyme's natural antimicrobial activity is well-established scientifically, the practical benefit of this ingredient in typical skincare concentrations has not been extensively documented in clinical studies. It is generally regarded as a safe, gentle conditioning agent rather than a targeted treatment for specific skin concerns.

How to Use

Lysozyme is typically incorporated into cleansers, serums, and moisturisers as part of a broader formulation. There are no specific usage guidelines required, as it is a gentle supporting ingredient rather than an active treatment. Use products containing lysozyme as directed by the manufacturer.

Safety & Precautions

Lysozyme is generally well-tolerated and considered safe for topical use. Those with egg allergies should note that lysozyme is often derived from egg white, though the processed form used in cosmetics is unlikely to trigger reactions in most individuals. If concerned, patch test first.

Frequently Asked Questions

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