Madecassic Acid
INCI: MADECASSIC ACID
Reviewed by Daisy · Last updated 14 Aug 2026
A triterpene compound from gotu kola that supports skin conditioning and repair
Best For Skin Types
All, Sensitive, Dry
Addresses
Usage Frequency
Daily
What Is Madecassic Acid?
Madecassic acid is one of the key active compounds found in Centella asiatica (commonly known as gotu kola), a medicinal plant native to tropical and subtropical regions. It belongs to a group of molecules called pentacyclic triterpenes, which are the primary bioactive constituents responsible for the plant's traditional use in skincare and wound healing across Ayurvedic and Chinese medicine.
In skincare products, madecassic acid functions as a skin conditioning agent. It works as part of the plant's natural triterpene profile alongside related compounds like asiaticoside and asiatic acid, all of which contribute to the ingredient's reported benefits for skin health and resilience.
Benefits for Your Skin
How It Works
Madecassic acid is believed to work through multiple mechanisms within the skin. The triterpene structure allows it to penetrate the skin barrier and interact with underlying tissues, potentially stimulating the skin's natural repair and regeneration processes.
The compound may also support collagen formation and reduce inflammatory responses in the skin, though the exact pathways are still being studied. As part of the broader Centella asiatica profile, madecassic acid likely works synergistically with other triterpenes to produce its conditioning effects.
Clinical Evidence & References
Research on Centella asiatica and its triterpene constituents, including madecassic acid, shows promising results for wound healing, scar management, and general skin resilience. Studies indicate the plant extract supports the healing process for small wounds, burns, and hypertrophic scars, with effects documented in both laboratory and clinical settings.
However, most published research focuses on the whole plant extract or specific glycoside forms rather than madecassic acid in isolation. Evidence for madecassic acid as a standalone ingredient in cosmetic formulations is more limited, so benefits should be understood within the context of the broader Centella asiatica profile.
How to Use
Madecassic acid is typically found as part of Centella asiatica extracts in serums, toners, moisturisers and barrier repair products. Use as directed on product labels, generally once or twice daily. It pairs well with other soothing and hydrating ingredients, and can be incorporated into most skincare routines regardless of primary concerns.
Safety & Precautions
Frequently Asked Questions
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