Antioxidant

Morus Bombycis Extract

INCI: MORUS BOMBYCIS EXTRACT

Reviewed by Rosie · Last updated 14 Aug 2026

Also known as: Morus Bombycis Extract

A plant extract studied for its potential to inhibit melanin production and protect against oxidative stress

Best For Skin Types

All, Oily, Combination

Addresses

Hyperpigmentation, Uneven skin tone, Sensitivity

Usage Frequency

Daily

What Is Morus Bombycis Extract?

Morus bombycis extract is derived from the mulberry plant (Morus bombycis Koidzumi), native to East Asia. In skincare formulations, it functions as a multitasking ingredient with antioxidant, antimicrobial, and potential skin-conditioning properties.

The extract has been investigated primarily for its ability to interfere with tyrosinase, an enzyme involved in melanin synthesis. This mechanism makes it of interest to formulators working on hyperpigmentation concerns, though its effectiveness in finished skincare products depends on concentration and formulation stability.

Benefits for Your Skin

How It Works

Morus bombycis extract inhibits tyrosinase, the enzyme responsible for converting the amino acid tyrosine into melanin. By slowing this enzymatic pathway, the extract may reduce the amount of new melanin produced in the skin, potentially helping to prevent or lighten hyperpigmentation over sustained use.

The extract's antioxidant compounds also help protect skin cells from oxidative stress caused by environmental factors like UV exposure and pollution, which can otherwise trigger increased melanin production and accelerate visible ageing.

Clinical Evidence & References

In laboratory studies, Morus bombycis extract has shown notable inhibition of human tyrosinase activity, performing favourably compared to other plant extracts screened for this effect. Research indicates it inhibits both tyrosinase enzyme activity directly and can reduce melanin synthesis in melanoma cell cultures.

However, most evidence comes from in vitro (laboratory) studies rather than human clinical trials. Whilst the mechanisms are promising, real-world efficacy in finished skincare products will depend on concentration, pH, stability during storage, and individual skin variation. Further human studies would help establish meaningful concentrations and expected timelines for visible results.

How to Use

Morus bombycis extract is typically incorporated into serums, toners, or moisturisers rather than used alone. For hyperpigmentation concerns, consistent daily use is generally recommended, as tyrosinase inhibition works gradually and results become apparent over weeks to months. Combine with sun protection (SPF 30+) to prevent new pigmentation from forming, which is essential for any depigmenting routine.

Safety & Precautions

Morus bombycis extract is generally well-tolerated in cosmetic formulations. Those with known sensitivity to mulberry or other Moraceae plant family members should patch-test first. No significant safety concerns have been documented at typical cosmetic concentrations.

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