Best For Skin Types
All, Dry, Mature, Combination
Addresses
Usage Frequency
Daily
What Is Oligopeptide-22?
Oligopeptide-22 is a peptide—a short chain of amino acids—designed to function as a skin conditioning agent. Peptides are fragments of proteins that are small enough to penetrate the skin's outer layers, making them useful ingredients in cosmetic formulations.
This ingredient works primarily to improve skin texture and condition by interacting with the skin's natural structures. It is typically used in serums, moisturisers, and treatment products at concentrations that vary depending on the formulation.
How It Works
Oligopeptide-22 works by conditioning the skin—essentially improving its appearance and tactile quality. As a peptide, it is smaller than full-size proteins, which allows it to interact with the outer layers of the epidermis more readily than larger molecules.
The ingredient supports skin's natural functions by engaging with the skin's structural components. Because skin ages partly through a gradual loss of collagen and a thinning of the epidermis and dermis, ingredients that support skin conditioning may help maintain a more resilient and youthful appearance.
Clinical Evidence & References
Research into skin ageing demonstrates that the skin undergoes significant structural changes with time, including loss of dermal collagen and thinning of both epidermal and dermal layers. Peptides as a category have been studied for their potential to support skin structure and appearance, though the specific clinical evidence for Oligopeptide-22 in peer-reviewed literature is limited.
Most of what we know about this ingredient comes from its use in cosmetic formulations rather than extensive independent clinical trials. It is positioned as a conditioning agent that supports skin quality, but consumers should be aware that large-scale clinical studies specifically validating its efficacy are not readily available in published research.
How to Use
Oligopeptide-22 is typically found in serums and moisturisers where it can be applied to clean skin once or twice daily. For best results, apply to damp skin to support hydration, and allow the product to absorb before applying sunscreen or other products. It can be layered with other actives, though patch testing is sensible if you have sensitive skin.
Safety & Precautions
Frequently Asked Questions
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