Oxyquinoline Sulfate
INCI: OXYQUINOLINE SULFATE
Reviewed by Daisy · Last updated 14 Aug 2026
Also known as: Oxyquinoline Sulfate
A synthetic purifying that stabilises formulations and helps prevent microbial growth
Best For Skin Types
All
Usage Frequency
N/A — ingredient function is within formulation
What Is Oxyquinoline Sulfate?
Oxyquinoline Sulfate is the salt form of oxyquinoline, a synthetic heterocyclic compound used in cosmetics as a preservative and emulsion stabiliser. It functions as a biocide, meaning it works to inhibit the growth of microorganisms that could otherwise compromise product integrity or safety.
In skincare products, it serves a dual purpose: protecting the formula itself from bacterial and fungal contamination, and contributing to the stability of emulsified systems (products that blend oil and water-based ingredients).
How It Works
Oxyquinoline Sulfate acts as a preservative by inhibiting the growth of microorganisms within the product formulation. Its antimicrobial activity helps prevent contamination during manufacture, storage and use, which is particularly important in leave-on skincare products.
As an emulsion stabiliser, it also helps maintain the uniform texture and consistency of products that combine oil and water-based components, preventing separation or degradation over time.
Clinical Evidence & References
Safety data on Oxyquinoline Sulfate is limited in published research. Available animal studies suggest it exhibits low acute and subchronic toxicity, and the ingredient is metabolised and excreted relatively quickly. In Europe, it is accepted for use as a stabiliser for hydrogen peroxide in hair care preparations with specified concentration limits.
However, comprehensive clinical data on its efficacy and safety profile in skincare products remains sparse. Regulatory acceptance varies by region, and current use in cosmetics appears limited compared to other preservative systems.
How to Use
Oxyquinoline Sulfate is typically incorporated into formulations during manufacture rather than applied as a standalone treatment. If you use products containing this ingredient, follow the manufacturer's instructions for application. There is no evidence that higher concentrations improve efficacy; regulatory limits exist to ensure safety.
Safety & Precautions
Frequently Asked Questions
From the Clinic
Not sure what your skin actually needs?
Two minutes, a few questions, and we’ll point you at what matters — no guesswork.
Take the skin quizRelated Ingredients
Octenidine Hcl
A synthetic purifying agent used primarily in clinical wound care and antisepsis
Oenanthe Javanica Extract
A plant extract with purifying and antioxidant properties, traditionally used in skincare
Ovalicin
A fungal-derived compound investigated for its potential to reduce itching and inflammatory responses
P-Chloro-M-Cresol
A phenolic preservative that prevents microbial growth in cosmetic formulations
Permethrin
A topical purifying agent used to treat mite-related skin infestations
Phenol
A preservative and purifying agent used in skincare formulations
Learn More About Skincare Ingredients
Explore our comprehensive ingredient glossary to understand what's in your products.
Browse All IngredientsShop Our Products
Find professional skincare solutions at Skintique.