Preservative

Oxyquinoline Sulfate

INCI: OXYQUINOLINE SULFATE

Reviewed by Daisy · Last updated 14 Aug 2026

Also known as: Oxyquinoline Sulfate

A synthetic purifying that stabilises formulations and helps prevent microbial growth

Best For Skin Types

All

Usage Frequency

N/A — ingredient function is within formulation

What Is Oxyquinoline Sulfate?

Oxyquinoline Sulfate is the salt form of oxyquinoline, a synthetic heterocyclic compound used in cosmetics as a preservative and emulsion stabiliser. It functions as a biocide, meaning it works to inhibit the growth of microorganisms that could otherwise compromise product integrity or safety.

In skincare products, it serves a dual purpose: protecting the formula itself from bacterial and fungal contamination, and contributing to the stability of emulsified systems (products that blend oil and water-based ingredients).

How It Works

Oxyquinoline Sulfate acts as a preservative by inhibiting the growth of microorganisms within the product formulation. Its antimicrobial activity helps prevent contamination during manufacture, storage and use, which is particularly important in leave-on skincare products.

As an emulsion stabiliser, it also helps maintain the uniform texture and consistency of products that combine oil and water-based components, preventing separation or degradation over time.

Clinical Evidence & References

Safety data on Oxyquinoline Sulfate is limited in published research. Available animal studies suggest it exhibits low acute and subchronic toxicity, and the ingredient is metabolised and excreted relatively quickly. In Europe, it is accepted for use as a stabiliser for hydrogen peroxide in hair care preparations with specified concentration limits.

However, comprehensive clinical data on its efficacy and safety profile in skincare products remains sparse. Regulatory acceptance varies by region, and current use in cosmetics appears limited compared to other preservative systems.

How to Use

Oxyquinoline Sulfate is typically incorporated into formulations during manufacture rather than applied as a standalone treatment. If you use products containing this ingredient, follow the manufacturer's instructions for application. There is no evidence that higher concentrations improve efficacy; regulatory limits exist to ensure safety.

Safety & Precautions

Animal studies suggest low toxicity, and the ingredient is accepted for use in some regions under specified conditions. However, comprehensive human safety data is limited, and some regulatory bodies do not currently approve its use in cosmetics.

Frequently Asked Questions

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