Permethrin

Permethrin is a synthetic pyrethroid insecticide derived from natural compounds found in chrysanthemum flowers. In skincare, it functions as a topical antimicrobial agent specifically designed to target parasitic mites that burrow into or colonise the skin.The ingredient works by disrupting the nervous system of mites, rendering them unable to survive on the skin. It is not used for general skincare purposes but rather as a targeted treatment for specific mite-related skin conditions that require professional medical guidance.

Permethrin acts as a neurotoxin to parasitic mites. It disrupts the sodium channels in the mite's nervous system, causing paralysis and death. This mechanism is selective enough to affect mites whilst having minimal impact on human cells when used topically at appropriate concentrations.The ingredient requires proper application technique and timing to be effective. Current clinical guidance indicates that permethrin is considered first-line treatment for scabies, often applied as a topical cream or lotion to affected areas and sometimes the entire body, depending on the condition being tre…

Permethrin should only be used under medical guidance. Application instructions vary depending on the condition being treated and the specific formulation prescribed. Typically, the cream or lotion is applied to clean skin, allowed to dry, and left on the skin for a specified duration before washing off. Retreatment may be necessary after 7–14 days. All household members and close contacts may require treatment simultaneously to prevent reinfestation. Clothing, bedding, and personal items should be washed in hot water as part of the treatment protocol.

Permethrin is generally well-tolerated when used as directed. Mild localised irritation, burning or itching may occur at the application site. It should not be used on infants or very young children without medical supervision, and pregnant or breastfeeding individuals should consult their healthcare provider before use. If you're pregnant or breastfeeding, please check with us first — [email protected].