Palmitoyl Dipeptide-5 Diaminohydroxybutyrate
Reviewed by Rosie · Last updated 18 Aug 2026
Also known as: Peptides, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine
Synthetic peptide | Derived partly from palmitic acid
Addresses
EWG Safety Score
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What Is Palmitoyl Dipeptide-5 Diaminohydroxybutyrate?
Palmitoyl dipeptide-5 diaminohydroxybutyrate is a synthetic peptide creation from a reaction of the fatty acid palmitic and the amino acid derivative diaminohydroxybutyric acid with dipeptide-5. In cosmetics, its primary function is as a skin conditioning ingredient.
This peptide is featured as part of an ingredient blend called SYN®-TACKS CB that also includes water, glycerin, and palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine. Manufacturers of the blend claim it improves skin elasticity, firmness, and suppleness by strengthening the junction between the dermis and the epidermis.
In peptide blends, palmitoyl dipeptide-5 diaminohydroxybutyrate is generally used in amounts between 1-3%.
Clinical Evidence & References
Published Research
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SpecialChem, Website, Accessed October 2025 [URL_NOT_FOUND]
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UL Prospector, Website, Accessed October 2025 [URL_NOT_FOUND]
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National Institutes of Health, Website, Accessed October 2025 [URL_NOT_FOUND]
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Journal of Biomaterials & Functional Materials, April 2025, ePublication [URL_NOT_FOUND]
From the Clinic
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Palmitoyl Decapeptide-21
A peptide derivative designed to support skin conditioning and resilience
Palmitoyl Dipeptide-10
Brightening peptide targeting melanin production
Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine
Advanced peptide complex for comprehensive anti-ageing
Palmitoyl Dipeptide-52
A peptide derivative designed to support skin conditioning and resilience
Palmitoyl Dipeptide-7
A peptide derivative used in skincare formulations for skin conditioning
Palmitoyl Dipeptide-7 Maltoside Tripeptide-69
A peptide-derived humectant that helps skin retain moisture and maintain hydration
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