Peptides

Palmitoyl Lysyl S-Snail Oligopeptide-1 Amide Acetate

INCI: PALMITOYL LYSYL S-SNAIL OLIGOPEPTIDE-1 AMIDE ACETATE

Reviewed by Kate · Last updated 2 Jun 2026

Also known as: Palmitoyl Lysyl S-snail Oligopeptide-1 Amide Acetate

A peptide derived from snail secretion designed to condition and support skin barrier function

Best For Skin Types

All, Dry, Sensitive, Mature

Addresses

Dryness, Sensitivity, Barrier repair

Usage Frequency

Daily

What Is Palmitoyl Lysyl S-Snail Oligopeptide-1 Amide Acetate?

Palmitoyl Lysyl S-Snail Oligopeptide-1 Amide Acetate is a peptide ingredient derived from snail secretion filtrate. It combines a short chain of amino acids (oligopeptide) with a fatty acid (palmitoyl) attachment, which helps it penetrate and remain stable within the skin.

This ingredient functions primarily as a skin conditioner, working to improve the texture, hydration, and overall condition of the skin's surface and upper layers. The snail-derived component is chosen for its natural moisturising and protein-rich profile.

How It Works

The ingredient works by delivering amino acids and moisture-binding compounds to the skin's outer layers. The fatty acid component allows the peptide to integrate into the skin's lipid matrix, where it can support the natural proteins and structural elements that keep skin hydrated and resilient.

By conditioning the skin barrier, it helps maintain the skin's ability to retain water and protect against environmental stress, which can prevent transepidermal water loss and support overall skin health.

Clinical Evidence & References

Direct clinical studies on this specific ingredient are limited in published literature. However, snail secretion filtrate ingredients have been investigated in cosmetic research for their hydrating and soothing properties, with some evidence suggesting benefit for skin conditioning and minor irritation.

As a peptide conditioning agent, it aligns with established knowledge about how amino acids and peptides support skin barrier function, though robust efficacy data specific to this formulation would strengthen confidence in its benefits.

How to Use

This ingredient is typically found in serums, moisturisers, and hydrating essences. Apply to clean skin before heavier creams to allow the peptide to absorb effectively. It works well alongside other hydrating and barrier-supporting ingredients, and can be used daily as part of your routine. Patch test first if you have particularly sensitive skin.

Safety & Precautions

Generally well-tolerated in cosmetic formulations. Those with shellfish sensitivity should exercise caution given the snail-derived nature of the ingredient, though topical application carries minimal risk compared to ingestion.

Frequently Asked Questions

From the Clinic

Not sure what your skin actually needs?

Two minutes, a few questions, and we’ll point you at what matters — no guesswork.

Take the skin quiz

Learn More About Skincare Ingredients

Explore our comprehensive ingredient glossary to understand what's in your products.

Browse All Ingredients

Authorised Stockist

Official UK retailer

Tracked Delivery

Free UK shipping over £50

5 Star Rating

Trusted by thousands

Expert Advice

Free consultations