Addresses
EWG Safety Score
Palmitoyl Tetrapeptide-10 products at Skintique
View all →What Is Palmitoyl Tetrapeptide-10?
Palmitoyl tetrapeptide-10 is a cosmetic ingredient – a synthetic peptide – obtained through the reaction of palmitic acid and tetrapeptide-10. Lysine, threonine and phenylalanine are the amino acids whose sequence comprises this peptide. It is marketed under the trade names Crystalide™, which is a blend of the protein with carrier compounds, and SpecPed® P4T10P.
At the time of this writing, this peptide isn’t in wide use in cosmetics and there isn’t a breadth of independent research regarding its efficacy in skin care products. Its manufacturer claims palmitoyl tetrapeptide-10 promotes skin brightness and smoothness by speeding up skin’s shedding process.
The independent Cosmetic Ingredient Review considers palmitoyl tripeptide-10 a skin conditioning ingredient. Used on its own, the recommended concentration is 0.0006%.
Clinical Evidence & References
Published Research
-
UL Prospector, Website, Accessed February 2025 [https://www.ulprospector.com/]
-
Journal of Cosmetic Dermatology, December 2024, pages 4,325-4,333 [https://onlinelibrary.wiley.com/doi/10.1111/jocd.16529]
From the Clinic
Not sure what your skin actually needs?
Two minutes, a few questions, and we’ll point you at what matters — no guesswork.
Take the skin quizRelated Ingredients
Palmitoyl Sh-Tripeptide-3 Amide
A peptide derivative that supports skin hydration and barrier function
Palmitoyl Sh-Tripeptide-5 Norisoleucyl Sh-Nonapeptide-1
A peptide derivative studied for potential skin-conditioning and barrier support
Palmitoyl Tetrapeptide-1
A peptide signal that may support skin's natural firming mechanisms
Palmitoyl Tetrapeptide-12
A peptide derivative used in skincare to support skin conditioning and firmness
Palmitoyl Tetrapeptide-20
A peptide designed to support skin's antioxidant defences and promote melanin production
Palmitoyl Tetrapeptide-20 Amide
A peptide derivative designed to condition and support hair fibre structure
Learn More About Skincare Ingredients
Explore our comprehensive ingredient glossary to understand what's in your products.
Browse All IngredientsShop Our Products
Find professional skincare solutions at Skintique.