Plant Extracts

Perilla Frutescens Leaf Water

INCI: PERILLA FRUTESCENS LEAF WATER

Reviewed by Daisy · Last updated 14 Aug 2026

Plant extract with potential antioxidant and skin-soothing properties

Best For Skin Types

All

Addresses

Redness, Sensitivity, Oxidative stress

Usage Frequency

Daily

What Is Perilla Frutescens Leaf Water?

Perilla frutescens leaf water is an aqueous extract derived from the leaves of the perilla plant, a herb native to East Asia. In skincare formulations, it functions primarily as a masking agent—helping to improve the sensory profile of products—whilst also contributing botanical compounds to the formula.

The perilla plant contains bioactive constituents including luteolin and other polyphenols, which have been investigated for their effects on skin health. When used in skincare, the leaf water delivers these plant compounds in a lightweight, hydrating base.

How It Works

Perilla leaf contains polyphenolic compounds, particularly luteolin, which function as antioxidants. These molecules work by neutralising free radicals—unstable atoms that can damage skin cells and contribute to inflammation and premature ageing.

Additionally, animal studies suggest that perilla extracts may modulate inflammatory pathways in the skin, potentially reducing redness and irritation when applied topically.

Clinical Evidence & References

Research into perilla leaf extract is limited in human studies but shows some promising findings in animal models. A mouse study demonstrated that topical application of perilla leaf extract reduced skin tumour promotion, with an even stronger effect observed from its isolated compound luteolin. However, these results were obtained in a cancer prevention context and cannot be directly extrapolated to general skincare benefits.

A screening study of plant extracts identified perilla among those with inhibitory activity against tyrosinase, an enzyme involved in melanin production. This suggests potential for addressing uneven skin tone, though human clinical data is lacking. Further research in human subjects would help establish the ingredient's efficacy in typical skincare concentrations.

How to Use

Perilla leaf water is typically used as a supporting ingredient within formulations rather than as a standalone treatment. It works well in essences, toners, and hydrating serums. For best results, apply to clean skin before heavier creams or oils, allowing the water-based formula to absorb fully.

Safety & Precautions

Perilla frutescens is generally considered safe for topical use and is well-tolerated by most skin types. No significant adverse effects have been reported in cosmetic applications, though those with known sensitivities to botanical extracts should patch-test first.

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Part of a family

Perilla Frutescens Leaf Water is a variant of Perilla Ocymoides Seed Extract, the form you will most often see on an ingredients list.

A plant-derived antioxidant from perilla seed that helps protect skin from environmental stress

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