Perilla Frutescens Leaf Water
INCI: PERILLA FRUTESCENS LEAF WATER
Reviewed by Daisy · Last updated 14 Aug 2026
Plant extract with potential antioxidant and skin-soothing properties
Best For Skin Types
All
Addresses
Usage Frequency
Daily
What Is Perilla Frutescens Leaf Water?
Perilla frutescens leaf water is an aqueous extract derived from the leaves of the perilla plant, a herb native to East Asia. In skincare formulations, it functions primarily as a masking agent—helping to improve the sensory profile of products—whilst also contributing botanical compounds to the formula.
The perilla plant contains bioactive constituents including luteolin and other polyphenols, which have been investigated for their effects on skin health. When used in skincare, the leaf water delivers these plant compounds in a lightweight, hydrating base.
How It Works
Perilla leaf contains polyphenolic compounds, particularly luteolin, which function as antioxidants. These molecules work by neutralising free radicals—unstable atoms that can damage skin cells and contribute to inflammation and premature ageing.
Additionally, animal studies suggest that perilla extracts may modulate inflammatory pathways in the skin, potentially reducing redness and irritation when applied topically.
Clinical Evidence & References
Research into perilla leaf extract is limited in human studies but shows some promising findings in animal models. A mouse study demonstrated that topical application of perilla leaf extract reduced skin tumour promotion, with an even stronger effect observed from its isolated compound luteolin. However, these results were obtained in a cancer prevention context and cannot be directly extrapolated to general skincare benefits.
A screening study of plant extracts identified perilla among those with inhibitory activity against tyrosinase, an enzyme involved in melanin production. This suggests potential for addressing uneven skin tone, though human clinical data is lacking. Further research in human subjects would help establish the ingredient's efficacy in typical skincare concentrations.
How to Use
Perilla leaf water is typically used as a supporting ingredient within formulations rather than as a standalone treatment. It works well in essences, toners, and hydrating serums. For best results, apply to clean skin before heavier creams or oils, allowing the water-based formula to absorb fully.
Safety & Precautions
Frequently Asked Questions
From the Clinic
Not sure what your skin actually needs?
Two minutes, a few questions, and we’ll point you at what matters — no guesswork.
Take the skin quizPart of a family
Perilla Frutescens Leaf Water is a variant of Perilla Ocymoides Seed Extract, the form you will most often see on an ingredients list.
A plant-derived antioxidant from perilla seed that helps protect skin from environmental stress
Related Ingredients
Perilla Ocymoides Seed Extract
A plant-derived antioxidant from perilla seed that helps protect skin from environmental stress
Perilla Ocymoides Seed Oil
A plant oil that conditions and softens skin with a lightweight texture
Perilla Frutescens Leaf Extract
A traditional herb extract with emerging research into skin resilience and inflammatory response
Perilla Ocymoides Leaf Extract
A plant extract traditionally used to support skin's natural balance and resilience
Perilla Frutescens Extract
A traditional herb extract with emerging evidence for skin barrier support and antioxidant protection
Pelargonium Graveolens Leaf Oil
A fragrant essential oil with potential antioxidant and sun-protective properties
Learn More About Skincare Ingredients
Explore our comprehensive ingredient glossary to understand what's in your products.
Browse All IngredientsShop Our Products
Find professional skincare solutions at Skintique.