Best For Skin Types
All, Dry, Sensitive, Mature
Addresses
Usage Frequency
Daily
What Is Perilla Frutescens Seed Oil?
Perilla frutescens seed oil is a plant-derived oil extracted from the seeds of the perilla plant, native to East Asia. It is composed primarily of essential fatty acids—particularly linolenic acid, oleic acid, and linoleic acid—along with sterols and other lipid compounds that support skin health.
In skincare formulations, perilla seed oil functions as an emollient and skin conditioning agent. Its role is to soften the skin surface, improve moisture retention, and help maintain the structural integrity of the skin barrier through its fatty acid profile.
How It Works
Perilla seed oil works primarily through its composition of essential fatty acids (linolenic, oleic, and linoleic acids), which are structural components naturally found in healthy skin. These fatty acids are absorbed into the outer layers of the skin, where they help fill gaps in the stratum corneum and reduce transepidermal water loss.
The oil's sterols and antioxidant compounds may also support skin cells in managing oxidative stress—damage caused by free radicals and environmental factors like UV exposure. This is thought to occur at the cellular level, though human clinical evidence remains limited.
Clinical Evidence & References
In vitro and animal studies suggest perilla seed oil may support skin health during UV-induced stress. Research in human dermal fibroblasts (skin cells) and hairless mice models showed improvements in cell viability and antioxidant markers when perilla oil was applied alongside UV exposure. However, these findings are preliminary and do not indicate that the oil provides sun protection in place of dedicated sunscreens.
Evidence for perilla seed oil's broader benefits in human skin is still emerging. Whilst the fatty acid composition is well-understood from a biochemical perspective, more clinical studies in human volunteers would help clarify its practical benefits for different skin concerns.
How to Use
Perilla seed oil is typically used as part of a formulated product (serum, moisturiser, or emulsion) rather than applied as a pure oil on its own. Apply to clean, damp skin in the morning or evening, or as directed by the product instructions. It can be layered with other skincare steps and works well in both hydrating and barrier-support routines. If using pure oil, a small amount (two to three drops) is usually sufficient for the face.
Safety & Precautions
Frequently Asked Questions
From the Clinic
Not sure what your skin actually needs?
Two minutes, a few questions, and we’ll point you at what matters — no guesswork.
Take the skin quizRelated Ingredients
Pentaclethra Macrophylla Seed Oil
A plant-derived oil that conditions and softens the skin barrier
Pentaerythrityl Adipate …
A synthetic emollient that smooths texture and regulates product consistency
Pentaerythrityl Tetracaprylate/Tetracaprate
A synthetic emollient that softens and smooths the skin barrier
Persea Gratissima (Avocado) Oil
Persea Gratissima Cera
Plant-derived wax that softens and conditions the skin barrier
Persea Gratissima Fruit Butter
A plant-derived emollient that softens and conditions the skin
Learn More About Skincare Ingredients
Explore our comprehensive ingredient glossary to understand what's in your products.
Browse All IngredientsShop Our Products
Find professional skincare solutions at Skintique.