Emulsifier

Poloxamer 188

INCI: POLOXAMER 188

Reviewed by Daisy · Last updated 14 Aug 2026

A solubilising agent that helps bind water and oil-based ingredients in skincare formulations

Best For Skin Types

All, Oily, Dry, Combination, Sensitive, Mature, Acne-prone

Addresses

Formulation consistency

Usage Frequency

Daily

What Is Poloxamer 188?

Poloxamer 188 is a synthetic polymer derived from ethylene oxide and propylene oxide. It belongs to a class of ingredients called poloxamers, which are widely used in pharmaceuticals and cosmetics as emulsifiers and surfactants.

In skincare, its primary role is to help blend water and oil-based components that would otherwise separate. This allows formulators to create stable, uniform products with improved texture and consistency.

How It Works

Poloxamer 188 is an emulsifier with a unique molecular structure: one end attracts water while the other attracts oil. This allows it to position itself at the interface between incompatible ingredients, holding them together and preventing them from separating.

Beyond emulsification, research in clinical settings has explored poloxamer-based hydrogels as delivery systems for therapeutic agents in wound care, suggesting it may also play a supporting role in maintaining skin hydration and product efficacy when incorporated into more complex formulations.

Clinical Evidence & References

Most published research on poloxamer 188 in skincare focuses on its use within hydrogel matrices rather than as a standalone skincare ingredient. Studies have examined poloxamer F-127 (a variant) combined with stem cell-derived compounds and other active agents for wound healing and skin regeneration in clinical settings.

While these results are promising for therapeutic applications, evidence specific to its use in everyday skincare formulations remains limited. Its primary function in cosmetics remains well-established: as a reliable, well-tolerated emulsifier that has been used safely for decades.

How to Use

Poloxamer 188 is used at low concentrations within finished products, so there are no specific usage instructions to follow. Simply use your formulation as directed. Its presence will not affect how you apply your skincare routine, though it contributes to the overall stability and feel of the product.

Safety & Precautions

Poloxamer 188 is generally well-tolerated and has a long safety history in both pharmaceuticals and cosmetics. It is suitable for most skin types, including sensitive skin, though individual sensitivities remain possible.

Frequently Asked Questions

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Part of a family

Poloxamer 188 is a variant of Poloxamer 338, the form you will most often see on an ingredients list.

A synthetic emulsifier that stabilises formulations and enables ingredient delivery

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