Best For Skin Types
All
Usage Frequency
As directed by product instructions
What Is Poly 1,2-Butanediol-6 Propylene Glycol?
Poly 1,2-butanediol-6 propylene glycol is a synthetic polymer that functions primarily as a solvent in skincare formulations. It is composed of repeating units of butanediol and propylene glycol, both humectant compounds that have been used safely in cosmetics for decades. This ingredient helps dissolve other actives and ingredients that would otherwise be poorly soluble, enabling formulators to create stable, effective products.
By improving the solubility of active ingredients, this polymer allows formulators to achieve higher concentrations of beneficial compounds in a single product without compromising stability or texture. It is typically used in leave-on formulations where its solvent properties support ingredient efficacy.
How It Works
This ingredient works by dissolving poorly soluble compounds through its chemical structure, which contains both hydrophobic (water-repelling) and hydrophilic (water-attracting) regions. This dual nature allows it to interact with a wide range of active ingredients, breaking them down into smaller, more bioavailable forms that the skin can better utilise.
When incorporated into a formulation, it maintains the dissolved state of these actives, preventing them from separating or crystallising out over the product's shelf life. This ensures that the active ingredients remain stable and effective throughout use.
Clinical Evidence & References
Research exploring propylene glycol and related polymers suggests they play an important role in enhancing the delivery of poorly soluble active ingredients, including pharmaceutical compounds. Studies examining drug delivery systems have shown that polymers in this class can improve permeation and bioavailability of actives across biological membranes.
However, specific clinical evidence for this particular polymer formulation's direct skin benefits is limited in published literature. Its primary value lies in its functional role as a solvent rather than as an active ingredient in its own right. The skincare benefits depend largely on the actives it helps deliver.
Published Research
How to Use
This ingredient is typically used as a supporting component rather than a standalone active, so its presence alone is not the key consideration. Look at the complete formulation and the active ingredients it is helping to solubilise. Use products containing this ingredient as directed by the brand, typically as part of your regular skincare routine.
Safety & Precautions
Frequently Asked Questions
From the Clinic
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Phenylpropanol
A fragrance compound that masks odour and adds scent to skincare formulations
Phospholipids
Occur naturally in skin and can be derived from plant and animal sources | Are hygroscopic, meaning they attract water from surrounding air and hold it where hydration is needed
Pinus Palustris Wood Tar
A wood-derived denaturant used to render other ingredients unsuitable for consumption
PPG-6
A humectant and solvent that helps formulations blend whilst supporting skin hydration
Propanediol
Also known as 1,3-propanediol | Improves absorption of ingredients to their boost effectiveness in skin
Purified Water
Purified water is a commonly used solvent, often appearing first
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