Solvent

Propanediol

Reviewed by Rosie · Last updated 18 Aug 2026

Also known as: 1, 3-propanediol

Also known as 1,3-propanediol | Improves absorption of ingredients to their boost effectiveness in skin

Addresses

Dehydration

What Is Propanediol?

Propanediol (also known as 1,3-propanediol) is a glycol that can increase the absorption of ingredients (such as salicylic acid) to improve their effectiveness. Additionally, it offers moisturizing properties that can result in a smooth, dewy finish as the formula sets. Propanediol is a considered a safe, well-tolerated ingredient, not likely to cause sensitivity.

Propanediol is a versatile ingredient with additional properties that make it a favorable choice in skin care products, including its ability to boost the effectiveness of a preservative system within a formula. It can also serve as a solvent in a blend of ingredients.

Propanediol can be derived naturally from corn or created synthetically. It is a colorless to pale yellow, viscous (somewhat sticky) liquid and is chemically similar to 1,2-propanediol (propylene glycol).

In June 2018 the Cosmetic Ingredient Review Board reevaluated propanediol’s use in personal care products and concluded that propanediol is safe. For leave-on products it was recorded in up to a 39.9% concentration (for a deodorant) - skin care products generally contain lower amounts than that.

Benefits for Your Skin

Clinical Evidence & References

Published Research

  • PubChem Compound Summary, April 2021, ePublication [https://pubchem.ncbi.nlm.nih.gov/compound/1_3-Propanediol]
  • SpecialChem, Accessed April 2021, ePublication [https://www.specialchem.com/cosmetics/inci-ingredients/propanediol]
  • Cosmetic Ingredient Review, June 2018, pages 1-73 [https://www.cir-safety.org/sites/default/files/aldiol032018FR.pdf]
  • Cosmetics & Toiletries, May 2013, pages 81-86 [https://www.cosmeticsandtoiletries.com/testing/method-process/article/21835183/evaluating-13propanediol-for-potential-skin-effects]

From the Clinic

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Other forms of Propanediol

These appear on ingredients lists under different names but are the same substance. Propanediol is the common form.

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