Skin Conditioning

Polylysine

INCI: Epsilon-Polylysine

Reviewed by Emma · Last updated 18 Aug 2026

Also known as: EPL, Natural Antimicrobial Peptide

Natural purifying for preservation and skin health

Addresses

acne, bacteria, preservation, skin clarity

What Is Polylysine?

Epsilon-polylysine is a naturally occurring antimicrobial peptide produced by fermentation of Streptomyces albulus. It has been used in food preservation and is gaining popularity in skincare.

The peptide provides broad-spectrum antimicrobial activity against bacteria, yeast, and fungi. It can serve as both an active ingredient and a natural preservative.

Polylysine is gentle enough for use on skin while providing effective protection against microorganisms.

How widely it's used

0.1%
of skincare products contain this ingredient .
Most common in: Treatments Cleansers Moisturisers

Regulatory information

Standardised cosmetic-ingredient identifiers used by regulators.

Show identifiers
INCI Name
POLYLYSINE
EC Number
-
Function
Hair Conditioning

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