Polyquaternium-22
INCI: POLYQUATERNIUM-22
Reviewed by Emma · Last updated 14 Aug 2026
A film-forming polymer that helps reduce static and improves product texture
Best For Skin Types
All, Oily, Dry, Combination, Sensitive, Mature, Acne-prone
Effective Concentrations
Up to 2%
Usage Frequency
Daily
What Is Polyquaternium-22?
Polyquaternium-22 is a synthetic polymer—a large, charged molecule made up of many smaller units linked together. It belongs to a family of ingredients widely used in cosmetics for their ability to improve how products feel and perform on the skin and hair.
In skincare formulations, polyquaternium-22 primarily functions as an antistatic agent and film former. This means it helps reduce static electricity and can create a light, even layer on the skin, contributing to smoother texture and improved product spreadability.
How It Works
Polyquaternium-22 works by forming a thin, protective layer on the skin's surface. Its charged molecular structure allows it to bind to skin and create a smooth film, which reduces static electricity that might otherwise cause discomfort or product pilling.
Because it is a large, polar molecule, it remains primarily on the skin's surface rather than penetrating deeply, making it suitable for a wide range of formulations.
Clinical Evidence & References
Safety assessments have found polyquaternium-22 to be well-tolerated at typical use concentrations. The ingredient showed no skin irritation or sensitisation in available studies, and unreacted monomer content is considered low and of minimal concern.
However, comprehensive data on long-term effects and certain toxicity endpoints remain limited, which is not unusual for large polymeric ingredients that are not readily absorbed by the skin. Current evidence supports its safe use in cosmetic products.
How to Use
Polyquaternium-22 is typically used as a supporting ingredient rather than an active, so it is most effective as part of a well-formulated product rather than as a standalone treatment. Look for it in serums, moisturisers, and lightweight textures where improved spreadability and comfort are desired. It can be used daily as part of your regular skincare routine.
Safety & Precautions
Frequently Asked Questions
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