Polyquaternium-37
INCI: POLYQUATERNIUM-37
Reviewed by Kate · Last updated 14 Aug 2026
A conditioning polymer that smooths hair texture and reduces static
Best For Skin Types
All, Oily, Combination
Usage Frequency
Daily
What Is Polyquaternium-37?
Polyquaternium-37 is a synthetic conditioning polymer derived from quaternised cellulose or similar plant-based compounds. It belongs to a family of cationic (positively charged) polymers commonly used in personal care formulations.
In skincare, it functions primarily as an antistatic agent and film former. When applied to the skin, it creates a light protective layer that helps reduce friction and imparts a smoother feel to the skin surface.
How It Works
Polyquaternium-37 works through electrostatic attraction. Its positive charge adheres to the negatively charged outer layer of skin cells, forming a thin, invisible film. This coating smooths surface irregularities and reduces the friction that causes static sensation.
The polymer is designed to be light and non-occlusive, so it doesn't create a heavy seal. Instead, it sits on the outermost layers, providing a temporary smoothing effect that typically lasts until the next cleanse.
Clinical Evidence & References
Published clinical data specifically on polyquaternium-37 in skincare is limited. Most evidence comes from cosmetic chemistry and sensory evaluation studies rather than dermatological trials. The ingredient has a long history of safe use in hair and personal care products, which supports its continued use in formulations.
Its efficacy as a smoothing and antistatic agent is well-established in cosmetic science, though individual results may vary depending on formulation and skin condition.
How to Use
Polyquaternium-37 is typically used in leave-on products such as serums, lightweight moisturisers, or primer-type formulations. It works best when applied to clean, damp or dry skin. Because it forms a surface layer, it may feel slightly different on very dehydrated skin; pairing it with a hydrating base product can help. Allow 1–2 minutes for the film to set before applying makeup or additional products.
Safety & Precautions
Frequently Asked Questions
From the Clinic
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