R-Spider Polypeptide-1
INCI: R-SPIDER POLYPEPTIDE-1
Reviewed by Emma · Last updated 18 Aug 2026
What Is R-Spider Polypeptide-1?
r-Spider Polypeptide-1 is a single chain recombinant spider protein, produced by fermentation in E. coli. The starting gene is directly isolated from Araneus diadematus which codes for Fibroin-3. The protein contains a maximum of 636 amino acids and consists of the proper sequence of the 20 standard amino acids.
Its declared cosmetic functions are hair conditioning, nail conditioning and skin protecting.
Source: European Commission CosIng inventory.
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