Prebiotic/Probiotic/Postbiotic

Saccharomyces Lysate Extract

INCI: SACCHAROMYCES LYSATE EXTRACT

Reviewed by Daisy · Last updated 2 Jun 2026

Also known as: Saccharomyces Lysate Extract

A fermented yeast extract that supports skin hydration and conditioning

Best For Skin Types

All, Dry, Sensitive

Addresses

Dryness, Hydration, Sensitivity

Usage Frequency

Daily

What Is Saccharomyces Lysate Extract?

Saccharomyces Lysate Extract is derived from Saccharomyces cerevisiae, a type of yeast commonly used in fermentation. The yeast cells are broken down (lysed) to release their cellular contents, creating an extract rich in amino acids, polysaccharides, and other bioactive compounds.

In skincare formulations, this ingredient functions primarily as a humectant and skin conditioner. Humectants work by drawing moisture into the outer layers of the skin, helping to improve hydration and maintain a smoother skin surface. The extract also provides amino acids that support the skin's natural moisturising factors.

Benefits for Your Skin

How It Works

The lysate extract contains several components that work together to improve skin hydration. Amino acids and small peptides penetrate the outer skin layers and contribute to the natural moisturising factor (NMF)—a mixture of compounds that helps skin retain water. The polysaccharides in the extract also act as humectants, binding water molecules and preventing transepidermal water loss.

Additionally, the bioactive compounds in yeast lysate may have mild conditioning properties that help improve skin texture and elasticity over time.

Clinical Evidence & References

Research on Saccharomyces Lysate Extract in skincare is limited. Most published studies focus on the antimicrobial or antioxidant properties of yeast-derived compounds in laboratory settings, rather than their effects in cosmetic formulations on human skin.

Evidence for its humectant and conditioning benefits is largely based on the known properties of its constituent amino acids and polysaccharides, rather than dedicated clinical trials. More human studies would be needed to establish the ingredient's efficacy in skincare products at typical use concentrations.

How to Use

This ingredient is typically found in serums, essences, and moisturisers at low concentrations (usually under 1%). It works well in layered hydration routines—apply it to clean, slightly damp skin before your other skincare products to optimise moisture absorption. It pairs well with other humectants like glycerin or hyaluronic acid.

Safety & Precautions

Saccharomyces Lysate Extract is generally well-tolerated and suitable for most skin types, including sensitive skin. Those with yeast sensitivities should patch test first.

Frequently Asked Questions

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