Sinorhizobium Meliloti Ferment Filtrate
Reviewed by Rosie · Last updated 18 Aug 2026
Also known as: SMFF, Sinorhizobium Ferment Filtrate, Subliskin
Biofermented ingredient | Moisturises and smoothes skin
Addresses
EWG Safety Score
What Is Sinorhizobium Meliloti Ferment Filtrate?
Sinorhizobium Meliloti Ferment Filtrate is a unique, biofermented ingredient derived from the microorganism Sinorhizobium meliloti. It is primarily known for its skin conditioning properties, helping to maintain the skin in good condition by improving its appearance and texture. The ingredient is a key component of the commercial product Subliskin™ by Sederma. It functions by acting on keratinocytes to stimulate the synthesis of key dermal components, notably hyaluronic acid and laminin-5. This stimulation leads to a chain reaction that also induces elastin synthesis in dermal fibroblasts, which helps to improve skin resilience, firmness, and smoothness. It is particularly beneficial for thin, fragile, and damaged skin, providing comfort and reinforcement against external aggressions.
Clinical Evidence & References
Published Research
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Sederma. Subliskin™ by Sederma (part of Croda, Inc) [https://www.ulprospector.com/en/na/PersonalCare/Detail/1240/109882/Subliskin]
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WO2010067327A1, Cosmetic composition containing acetylated oligoglucuronans [https://patents.google.com/patent/WO2010067327A1/en]
Frequently Asked Questions
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