Sodium Isethionate
Reviewed by Rosie · Last updated 18 Aug 2026
Also known as: sodium 2-hydroxyethyl sulfonate
Used as a surfactant | Becomes a detergent when it contacts oleic acid
Addresses
EWG Safety Score
What Is Sodium Isethionate?
Sodium isethionate, also known as sodium 2-hydroxyethyl sulfonate, is a synthetic ingredient used as a surfactant (surface active agent) in cosmetics. Surfactants interact with both water and other substances like oil and dirt, allowing them to act as detergents and foaming agents (they also help substances spread more easily). Sodium isethionate in particular forms a mild detergent when it comes into contact with oleic acid. Detergents are a type of surfactant, but otherwise the term “surfactant” has a broader meaning. The independent Cosmetic Ingredient Review board has ruled sodium isethionate safe as used in cosmetics, where its maximum usage concentration range is between 0.8%-6%.
Clinical Evidence & References
Published Research
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PubChem, Website, Accessed April 2025 [https://pubchem.ncbi.nlm.nih.gov/compound/Sodium-Isethionate]
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Ataman Chemicals, Website, Accessed April 2025 [https://www.ataman-chemicals.com/en/products/sodium-isethionate-6272.html]
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International Journal of Toxicology, May-June 2017, pages 5S-16S [https://journals.sagepub.com/doi/10.1177/1091581816685552]
Frequently Asked Questions
From the Clinic
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