Peptides

Sr-Cat Polypeptide-2

INCI: SR-CAT POLYPEPTIDE-2

Reviewed by Kate · Last updated 2 Jun 2026

Also known as: Sr-cat Polypeptide-2

A peptide that supports skin structure and antioxidant defence

Best For Skin Types

All, Mature

Addresses

Fine lines, Loss of elasticity, Environmental damage

Usage Frequency

Daily

What Is Sr-Cat Polypeptide-2?

Sr-Cat Polypeptide-2 is a peptide—a short chain of amino acids—designed to mimic and support natural skin proteins involved in cellular structure and protection. Peptides work by signalling to skin cells, potentially encouraging them to maintain or strengthen their structural components.

This ingredient functions primarily as an antioxidant and skin protectant, helping to defend against environmental stressors. It is also used in hair care formulations for conditioning properties, though its skincare applications are the focus here.

Benefits for Your Skin

How It Works

Sr-Cat Polypeptide-2 works through two primary mechanisms. As an antioxidant, it helps neutralise free radicals—unstable molecules that can damage skin cells and accelerate visible ageing. This protective action may reduce oxidative stress in the skin.

Additionally, this peptide is thought to communicate with skin cells, signalling the importance of maintaining structural proteins. This may help support the integrity of the skin's matrix, which naturally weakens over time and with environmental exposure.

Clinical Evidence & References

Research into lamin-associated polypeptides (the protein family this ingredient relates to) suggests these molecules play a role in cellular structure and stability within skin. Studies indicate that levels of these proteins decline with age, which correlates with changes in skin texture and firmness, though direct clinical data on Sr-Cat Polypeptide-2 specifically in cosmetic products remains limited.

The antioxidant and skin-protective functions are supported by the ingredient's chemical profile, but robust independent studies demonstrating visible results in human skin would strengthen the evidence base. Current use suggests tolerability and perceived benefits, though more targeted research would help clarify its efficacy in skincare formulations.

How to Use

Sr-Cat Polypeptide-2 is typically found in serums, moisturisers, and treatment products. For best results, apply to clean skin before moisturiser, or layer into your existing routine. As with most peptide ingredients, consistent daily use is more beneficial than sporadic application, as peptides work gradually to support skin function over time.

Safety & Precautions

Sr-Cat Polypeptide-2 is generally well-tolerated in skincare formulations. Those with known sensitivities to peptides or amino acids should patch-test before full application.

Frequently Asked Questions

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