Peptides

Sr-Cat Polypeptide-3

INCI: SR-CAT POLYPEPTIDE-3

Reviewed by Emma · Last updated 2 Jun 2026

Also known as: Sr-cat Polypeptide-3

A peptide with antioxidant and skin-conditioning properties

Best For Skin Types

All

Addresses

Sensitivity, Environmental damage, Barrier repair

Usage Frequency

Daily

What Is Sr-Cat Polypeptide-3?

Sr-Cat Polypeptide-3 is a peptide—a short chain of amino acids—designed to function as an antioxidant and skin protectant in skincare formulations. Peptides are increasingly used in cosmetic chemistry because they are relatively small molecules that can penetrate the skin's outer layers, potentially influencing skin condition and appearance.

This ingredient serves multiple functions: it helps neutralise free radicals that can damage skin cells, conditions the skin barrier, and provides protective benefits against environmental stressors. It is typically found in serums, moisturisers, and targeted treatment products.

Benefits for Your Skin

How It Works

Sr-Cat Polypeptide-3 works primarily as a free radical scavenger. Free radicals are unstable molecules that form when skin is exposed to environmental stressors; they can damage cell structures and accelerate visible ageing. As an antioxidant, this peptide donates electrons to neutralise these free radicals, reducing their potential to cause harm.

The peptide also interacts with the skin's outer layers to enhance hydration retention and strengthen the skin barrier. This dual action—protecting against oxidative damage whilst improving moisture retention—contributes to a more resilient, conditioned skin appearance.

Clinical Evidence & References

The research base for Sr-Cat Polypeptide-3 specifically in cosmetic applications is limited. While peptides as a category have demonstrated potential in skincare—particularly for antioxidant and barrier-support functions—individual peptides vary in their efficacy and the evidence supporting their use.

General peptide research suggests benefits in skin conditioning and protection, though the strength of evidence varies depending on concentration, formulation stability, and skin type. If you have specific skin concerns or sensitivities, it is worth observing how your skin responds over several weeks of consistent use, as individual results can vary.

How to Use

Sr-Cat Polypeptide-3 is best used as part of a layered routine. Apply it to clean skin, either in a serum or moisturiser, before heavier creams or oils. It pairs well with other antioxidants (such as vitamin C or niacinamide) and works in both morning and evening routines. Consistent use over several weeks will give the clearest sense of its effects on your skin.

Safety & Precautions

Sr-Cat Polypeptide-3 is generally well-tolerated in skincare formulations. As with any ingredient, patch test before widespread use if you have very sensitive skin or are prone to reactions.

Frequently Asked Questions

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