Peptides

Sr-Staphylococcus Simulans Polypeptide-1

INCI: SR-STAPHYLOCOCCUS SIMULANS POLYPEPTIDE-1

Reviewed by Emma · Last updated 2 Jun 2026

Also known as: Sr-staphylococcus Simulans Polypeptide-1

A bacterial-derived peptide with potential skin-conditioning properties

Best For Skin Types

All

Addresses

Hydration

Usage Frequency

Daily

What Is Sr-Staphylococcus Simulans Polypeptide-1?

Sr-Staphylococcus Simulans Polypeptide-1 is a peptide derived from Staphylococcus simulans, a naturally occurring bacterium. It belongs to a category of fermentation-derived ingredients increasingly used in skincare formulations for their potential bioactive properties.

As a polypeptide, this ingredient consists of amino acid chains that may interact with skin cells to support skin health. However, detailed information about its specific mechanism and function in skincare remains limited in public scientific literature.

How It Works

Peptides generally work by signalling to skin cells or forming a protective layer on the skin surface. This particular peptide, being derived from bacterial fermentation, may offer skin-conditioning benefits through film-forming properties or by providing amino acids that support skin structure.

The exact mechanism by which Sr-Staphylococcus Simulans Polypeptide-1 interacts with skin is not well documented in accessible research, so its precise function in formulations remains somewhat opaque.

Clinical Evidence & References

Published clinical research specifically evaluating Sr-Staphylococcus Simulans Polypeptide-1 is not readily available. The ingredient appears to be used primarily for its skin-conditioning properties based on industry experience rather than extensive human trials.

Peptide ingredients more broadly have demonstrated benefit in skincare, but evidence for this particular ingredient would benefit from further study to substantiate specific claims about efficacy.

How to Use

This ingredient is typically found in serums, moisturisers and treatment products. Use as directed by the specific product formulation. It pairs well with other hydrating and barrier-supporting ingredients, and is generally suitable for layering within a skincare routine.

Safety & Precautions

Generally well-tolerated; no significant safety concerns have been widely reported. Those with sensitivity to fermented ingredients should patch-test first.

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