Vitis Vinifera Seed
INCI: VITIS VINIFERA SEED
Reviewed by Rosie · Last updated 14 Aug 2026
Also known as: Vitis Vinifera Seed
A plant-derived conditioning agent rich in polyphenols from grape seeds
Best For Skin Types
All
Addresses
Usage Frequency
Daily
What Is Vitis Vinifera Seed?
Vitis vinifera seed is derived from grape seeds, a byproduct of wine and juice production. It contains a concentrated profile of polyphenolic compounds, including flavonoids, catechins, anthocyanins and resveratrol, which are plant compounds known for their antioxidant properties.
In skincare formulations, this ingredient functions primarily as a skin conditioner, helping to maintain skin texture and support the skin's outer layers. It is typically used in relatively modest concentrations within broader formulations.
How It Works
The ingredient works through its polyphenolic compounds, which have antioxidant activity in biological systems. These compounds can neutralise free radicals—unstable molecules that contribute to oxidative stress and premature skin ageing.
When applied topically, grape seed polyphenols are thought to exert their effects on the skin's surface and outer layers, helping to condition and support skin health through their antioxidant properties.
Clinical Evidence & References
Research indicates that Vitis vinifera seed extracts possess antioxidant activity due to their polyphenol content, particularly flavonoids and resveratrol. Most evidence comes from in vitro (laboratory) studies and animal models rather than robust human clinical trials on topical application.
Whilst the antioxidant potential is supported by phytochemical research, evidence for specific efficacy in skincare remains limited. The ingredient appears most useful as one component in a broader formulation designed to support skin health.
Published Research
How to Use
Vitis vinifera seed is typically found in serums, moisturisers and treatment products rather than as a standalone ingredient. It integrates well into antioxidant-focused skincare routines. Use as directed by the product formulation, which will determine optimal frequency and layering with other products.
Safety & Precautions
Frequently Asked Questions
From the Clinic
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Vitis Vinifera Fruit Cell Extract
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Vitis Vinifera Fruit Extract
A polyphenol-rich grape extract that helps protect skin from oxidative stress
Vitis Vinifera Leaf Extract
A plant extract that may help support skin resilience and reduce inflammatory responses
Vitis Vinifera Stem Extract
A polyphenol-rich plant extract that conditions and protects the skin
Vitis Vinifera Vine Extract
A plant extract that conditions and supports skin's natural moisture balance
Vitis Vinifera Vine Sap
A plant-derived conditioning agent that helps maintain skin hydration and softness
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