SkinCeuticals Triple Lipid Restore 2:4:2 | Anti-Ageing Cream | 48ml

Additional Product Information

Size: 48ml / 1.6 fl oz

Texture: Rich yet lightweight cream with fast-absorbing, non-greasy finish

Skin Type Suitability: Normal, dry, combination, oily, sensitive, dehydrated, and ageing skin

Clinical Testing: 8-week dermatologist-controlled clinical study on 55 female subjects aged 55-75, plus lipidomic analysis demonstrating lipid replenishment

Free-From Claims: Paraben-free, dye-free, non-comedogenic

Packaging: Airless jar packaging to maintain formula stability and efficacy

Special Notes

Certifications: US Patent No. 10,137,073 for unique 2:4:2 lipid formulation

Free-From Status: Formulated without parabens, dyes, or fragrance (essential oils provide subtle scent)

Storage Requirements: Store in a cool, dry place away from direct sunlight. Once opened, most effective when used within 12 months

Unique Features: First 2:4:2 cholesterol-dominant ratio cream; clinically proven to shorten retinoid adjustment period; non-comedogenic despite rich texture

How To Use

Application: Apply a small amount (approximately a pea-sized amount) between fingertips. Warm and melt the cream using gentle circular motions to activate the lipid-rich formula before spreading evenly across the face, neck, and chest.

Frequency: Use once or twice daily for optimal results. Can be incorporated into both morning and evening skincare routines.

Timing: In the morning, apply after cleansing, toning, and applying a SkinCeuticals vitamin C antioxidant serum, and before sunscreen application. In the evening, apply after cleansing and any treatment serums. If using retinol, apply Triple Lipid Restore 2:4:2 after retinol application to enhance tolerance and reduce irritation.

Layering: Compatible with all SkinCeuticals products. Layer under sunscreen during the day for optimal environmental protection. Can be used over retinoids at night to support barrier function during the adjustment period.

Expert Tips: For enhanced results with retinoids, use the "sandwiching method": apply a hydrating serum, then retinol, then finish with Triple Lipid Restore 2:4:2 to lock in moisture and support barrier integrity. Ideal for post-professional procedure care—consult our experts for personalised post-treatment guidance.

Full Ingredients List

Aqua/Water/Eau, Dimethicone, Hydrogenated Polyisobutene, Glycerin, Cholesterol, C12-15 Alkyl Benzoate, Ceramide 3, Helianthus Annuus Seed Oil Unsaponifiables/Sunflower Seed Oil Unsaponifiables, Bis-PEG-18 Methyl Ether Dimethyl Silane, Sodium Polyacrylate, PEG-10 Dimethicone, Nylon-12, Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone, Dimethicone/PEG-10/15 Crosspolymer, Phenoxyethanol, Disteardimonium Hectorite, Hydroxyethylpiperazine Ethane Sulfonic Acid, Ammonium Polyacryloyldimethyl Taurate, Chlorphenesin, Caprylyl Glycol, PEG/PPG-18/18 Dimethicone, Propylene Carbonate, Disodium EDTA, Acrylonitrile/Methyl Methacrylate/Vinylidene Chloride Copolymer, Adenosine, Dipropylene Glycol, Lavandula Angustifolia Oil/Lavender Oil, Rosmarinus Officinalis Leaf Oil/Rosemary Leaf Oil, T-Butyl Alcohol, Mentha Piperita Oil/Peppermint Oil, Sodium Citrate, Linalool, Isobutane, Ceramide EOP, BHT, Tocopherol, Limonene

Please note: Formulations are updated periodically by manufacturers without notice. Therefore, the ingredient lists on this website may differ from the product packaging depending on the time and country of purchase. Please refer to your product packaging for accurate ingredient lists. A patch test before use must be carried out for suitability.

FAQ

Q: How does Triple Lipid Restore 2:4:2 differ from a regular moisturiser?

A: Unlike conventional moisturisers that primarily provide surface hydration, Triple Lipid Restore 2:4:2 addresses the underlying cause of age-related dryness and barrier dysfunction. The patented 2:4:2 ratio of ceramides, cholesterol, and fatty acids replenishes the specific lipids that deplete with age, restoring barrier function at a cellular level. Clinical studies demonstrate measurable increases in skin's lipid content (57% increase in ceramides, 50% in cholesterol), resulting in sustained improvements in barrier resilience, hydration, and visible ageing signs that go far beyond temporary surface moisturisation.

Q: Can I use this product if I have oily or acne-prone skin?

A: Yes. Whilst the texture feels rich, Triple Lipid Restore 2:4:2 is non-comedogenic and suitable for all skin types, including oily and acne-prone skin. The formula actually helps improve barrier function, which enables skin to self-regulate oil production more effectively without creating excess sebum. Many individuals with oily skin experience barrier dysfunction, leading to compensatory oil production. By strengthening the lipid barrier, this cream can help balance skin without clogging pores. Adjust the amount used based on your skin's needs—oily skin types may require only a small amount, whilst dry skin may benefit from a more generous application.

Q: How long will it take to see results?

A: Results vary by individual, but clinical studies show measurable improvements within specific timeframes. Barrier resilience improves by 30% within just one week of use, with immediate hydration benefits noticeable within 24 hours. For visible improvements in smoothness, pore appearance, and radiance, most users notice changes within 2-4 weeks of consistent twice-daily application. The most significant results—including improvements in laxity and overall skin quality—are typically observed after 8 weeks of continued use, as demonstrated in clinical trials. Consistency is key to achieving optimal results.

Q: Can I use this cream with retinoids or other active treatments?

A: Absolutely. Triple Lipid Restore 2:4:2 is clinically proven to shorten the retinoid adjustment period by up to one week whilst reducing associated dryness and irritation. Apply your retinoid first, allow it to absorb, then apply Triple Lipid Restore 2:4:2 to seal in treatment and support barrier integrity. The "sandwiching method" (hydrating serum, retinoid, then Triple Lipid Restore) is particularly effective for maximising retinoid benefits whilst minimising irritation. This cream is also compatible with vitamin C serums, chemical exfoliants, and other professional-grade treatments. Speak to our experts for personalised layering guidance based on your specific routine.

Q: Is this product suitable for post-procedure skincare?

A: Many aesthetic professionals recommend Triple Lipid Restore 2:4:2 for post-procedure care due to its barrier-restoring and nourishing properties. The lipid-rich formula supports skin's natural healing processes following treatments such as chemical peels, microneedling, laser procedures, and aesthetic injections. However, always consult with your treating physician or our skincare experts for personalised post-procedure recommendations, as timing and application may vary depending on the specific treatment you've received.