Lactobionic Acid
Reviewed by Daisy · Last updated 14 Aug 2026
One of the polyhydroxy acids, chemically similar to AHAs Slower penetration means a gentler experience
EWG Safety Score
What Is Lactobionic Acid?
Lactobionic Acid is a type of polyhydroxy acid (PHA) that can exfoliate skin. It is chemically and functionally similar to AHAs (such as glycolic acid). The significant difference between lactobionic acid and AHAs is that lactobionic acid has a larger molecular structure, which limits its ability to penetrate the skin, resulting in less potential for stinging.
Polyhydroxy acids can also function as antioxidants and may promote some improvement in skin’s surface strength. Their antioxidant ability is due to being able to bind with (chelate) heavy metals that would otherwise damage skin. Lactic acid also has this benefit.
Typical usage levels of lactobionic acid in skin care range from 0.1–5%, with amounts above 3% considered necessary if the goal is exfoliation. Interestingly, research has shown no difference in skin response when a 10% and 30% concentration of lactobionic acid were compared as facial peels.
Low levels have been shown to help protect skin’s supportive elements from damage triggered by destructive enzymes. This benefit is tied to lactobionic acid’s ability to improve a sallow skin tone which can be a common visible trait on sun-damaged skin.
It is considered safe as used in cosmetics, and is an intriguing ingredient to consider if you have extra-sensitive, redness-prone skin.
Benefits for Your Skin
Clinical Evidence & References
- International Journal of Molecular Sciences, January 2021, pages 1–16
- Journal of Cosmetic Dermatology, December 2019, pages 1,705–1,710
- International Journal of Dermatology, March 2019, pages 374–379
- International Journal of Cosmetic Science, October 2012, pages 424–434
- The Journal of Clinical and Aesthetic Dermatology, May 2012, pages 32–40
- Dermatology Research and Practice, May 2021, pages 1–6
- Cutis, February 2004, pages 3–13
Frequently Asked Questions
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