Peptides

Barley Sh-Polypeptide-3

INCI: BARLEY SH-POLYPEPTIDE-3

Reviewed by Kate · Last updated 2 Jun 2026

Also known as: Barley Sh-polypeptide-3

A peptide derived from barley that conditions and supports skin texture

Best For Skin Types

All, Dry, Mature

Addresses

Dryness, Hydration, Fine lines

Usage Frequency

Daily

What Is Barley Sh-Polypeptide-3?

Barley SH-Polypeptide-3 is a peptide derived from barley, a cereal grain. Peptides are short chains of amino acids, the building blocks of proteins. This particular ingredient is classified as a skin-conditioning agent, meaning it works to improve the feel, appearance and hydration status of the skin's surface.

In formulations, it functions primarily as a humectant and film-former — helping skin retain moisture whilst creating a light protective layer on the skin barrier.

How It Works

Peptides like Barley SH-Polypeptide-3 work through two main mechanisms. First, they act as humectants, drawing water from the environment and deeper skin layers to the stratum corneum (outermost layer), which helps keep skin hydrated. Second, they form a lightweight occlusive film on the skin surface that reduces water loss.

The barley-derived peptide may also have mild film-forming properties that create a subtle smoothing effect, though research on this specific ingredient's mechanisms is limited in published literature.

Clinical Evidence & References

Published evidence specific to Barley SH-Polypeptide-3 in skincare is limited. Most data on peptide ingredients in general suggests they can improve hydration and skin texture when used consistently, though individual peptides have varying efficacy profiles.

Barley is commonly used in cosmetic formulations as a conditioning and soothing ingredient. However, we would benefit from more targeted clinical studies on this specific polypeptide to understand its optimal concentration, efficacy timeline and comparative performance against other peptide options.

How to Use

This ingredient is typically found in serums, moisturisers and hydrating essences. It works well in layered routines — apply to clean, damp skin before heavier moisturisers to maximise hydration benefits. It can be used daily as part of your morning and evening skincare routine.

Safety & Precautions

Barley SH-Polypeptide-3 is generally considered well-tolerated in topical skincare formulations. Those with known barley allergies or sensitivities should patch test first, though topical use is distinct from ingestion.

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