Peptides

Barley Sh-Polypeptide-17

INCI: BARLEY SH-POLYPEPTIDE-17

Reviewed by Daisy · Last updated 2 Jun 2026

Also known as: Barley Sh-polypeptide-17

A peptide derived from barley that conditions hair and skin

Best For Skin Types

All, Dry, Sensitive

Addresses

Dryness, Hydration, Barrier repair

Usage Frequency

Daily

What Is Barley Sh-Polypeptide-17?

Barley SH-Polypeptide-17 is a peptide—a short chain of amino acids—derived from barley grain. In cosmetic formulations, it functions primarily as a conditioning agent for both hair and skin.

Peptides are valued in skincare because they are small enough to potentially penetrate the outer layers of skin, where they may interact with structural proteins and support the skin's natural maintenance processes.

How It Works

As a peptide, barley SH-polypeptide-17 is composed of amino acids linked together in a specific sequence. When applied topically, these small molecules can penetrate into the outer layers of the skin more easily than larger proteins.

Once there, they may interact with skin cells and existing proteins, potentially supporting hydration and the appearance of skin firmness. The conditioning effect is thought to come from the peptide's ability to form a protective film on the skin's surface and help retain moisture.

Clinical Evidence & References

Direct clinical evidence on barley SH-polypeptide-17 specifically is limited in the published literature. Most research on peptides in skincare focuses on collagen, elastin, and other well-studied protein derivatives.

Peptides as a category have been shown in some studies to support skin hydration and elasticity, though the strength of evidence varies depending on the peptide, concentration, and study design. Without targeted research on this particular barley-derived peptide, claims about its efficacy should be treated with caution.

How to Use

Barley SH-polypeptide-17 is typically found in serums, moisturisers, and conditioners rather than as a standalone product. It works well in formulations alongside other hydrating and conditioning ingredients. There is no established limit to how often it can be used, and it can generally be incorporated into your routine daily.

Safety & Precautions

Generally well-tolerated in cosmetic formulations. Those with barley sensitivity or gluten concerns should note that whilst topical application is not the same as ingestion, a patch test is advisable if you have known cereal allergies.

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