Anti-Sebum

Cannabidiol - Synthetically Produced

INCI: CANNABIDIOL - SYNTHETICALLY PRODUCED

Reviewed by Emma · Last updated 14 Aug 2026

Also known as: Cannabidiol - Synthetically Produced

A non-psychotropic cannabinoid with potential antioxidant and soothing properties

Best For Skin Types

All, Oily, Sensitive

Addresses

Redness, Sensitivity, Oil control

Usage Frequency

Daily

What Is Cannabidiol - Synthetically Produced?

Cannabidiol (CBD) is a naturally occurring compound found in cannabis plants. In skincare, synthetically produced versions are used to avoid variability and ensure consistency. It functions as an antioxidant and skin-conditioning agent, working alongside the skin's own endocannabinoid system.

Unlike THC, CBD is non-psychotropic, meaning it does not produce a high. In formulations, it appears in very small concentrations and is incorporated primarily for its potential to support skin health rather than deliver dramatic transformations.

Benefits for Your Skin

How It Works

CBD interacts with the endocannabinoid system (ECS), a biological signalling network present in skin cells. This system plays a role in regulating immune function and inflammatory responses. By modulating ECS activity, CBD may help reduce excessive inflammation and support the skin's natural protective mechanisms.

As an antioxidant, it also helps neutralise harmful free radicals generated by UV exposure and environmental stressors, which can contribute to skin ageing and damage.

Clinical Evidence & References

Research into CBD's skin effects remains emerging. Preclinical studies show promise for anti-inflammatory activity, particularly in immune-mediated inflammatory conditions. One study examined CBD's effects on immune cells from individuals with psoriasis, suggesting immunomodulatory potential, though human skin studies are still limited.

Safety data from animal studies over 90 days showed CBD produced no adverse effects on blood count, organ function, or tissue morphology, indicating a favourable safety profile. However, robust clinical trials in human skin are needed to establish clear efficacy claims for specific skin concerns. The ingredient appears well-tolerated, but evidence of visible skin benefit remains preliminary.

How to Use

CBD is typically found in very low concentrations in skincare (under 0.1% of formulations), so it functions best as part of a broader routine rather than as a standalone solution. Use consistently as directed on the product label, whether in serums, moisturisers, or targeted treatments. Pair with proven actives such as retinol, niacinamide, or vitamin C for comprehensive skin support.

Safety & Precautions

CBD is generally well-tolerated with a favourable safety profile based on available evidence. As with any new ingredient, introduce it gradually and discontinue if irritation develops, particularly if you have very sensitive or compromised skin.

Frequently Asked Questions

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Cannabidiol - Synthetically Produced is a variant of Cannabidiol - Derived From Extract Or Tincture Or Resin Of Cannabis, the form you will most often see on an ingredients list.

A cannabinoid extract with antioxidant and skin-calming properties

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