Cannabis Sativa Extract
INCI: CANNABIS SATIVA EXTRACT
Reviewed by Rosie · Last updated 20 Jul 2026
Also known as: Cannabis Sativa Extract
Plant extract with potential soothing and antioxidant properties for skin health
Best For Skin Types
All, Oily, Combination, Sensitive
Addresses
Usage Frequency
Daily
What Is Cannabis Sativa Extract?
Cannabis sativa extract is derived from the cannabis plant and contains phytocannabinoids—naturally occurring compounds that interact with the skin's endocannabinoid system. Unlike the whole plant, cosmetic extracts are formulated to exclude THC (the psychoactive compound), focusing instead on non-intoxicating components like cannabidiol (CBD) and other beneficial phytochemicals.
In skincare formulations, cannabis sativa extract is used for its reported antimicrobial, antioxidant, and skin-protecting properties. The extract works through multiple pathways in the skin, some involving direct interaction with cannabinoid receptors and others through general anti-inflammatory mechanisms.
Benefits for Your Skin
How It Works
Cannabis sativa extract interacts with the skin through the endocannabinoid system—a biological network present in skin cells that regulates inflammation, immune function, and barrier health. The phytocannabinoids in the extract may activate cannabinoid receptors (CB1 and CB2) or work through other signalling pathways to reduce inflammatory mediators and promote skin balance.
The extract's antioxidant effects stem from its phytochemical composition, which includes compounds capable of neutralising reactive oxygen species that contribute to skin ageing and irritation. These mechanisms work synergistically to support skin health, though individual responses may vary.
Clinical Evidence & References
Research into cannabis sativa extract for skin health is emerging but still limited. Clinical and in vitro studies suggest potential benefits for acne, atopic dermatitis, psoriasis, and general skin irritation through anti-inflammatory and antioxidant mechanisms. However, most evidence comes from laboratory or small-scale studies rather than large-scale human trials.
Whilst the therapeutic potential is promising, robust clinical data in humans remains sparse. More rigorous studies are needed to establish efficacy, optimal concentrations, and long-term safety in skincare products. Current evidence supports further investigation rather than proven effectiveness for specific skin conditions.
How to Use
Cannabis sativa extract is typically found in serums, creams, and balms at varying concentrations. For best results, use consistently as directed on the product label. If combining with other actives (such as vitamin C or retinoids), introduce gradually to monitor skin tolerance. As with any botanical extract, patch testing is advisable if you have sensitive or reactive skin.
Safety & Precautions
If you’re pregnant or breastfeeding, please check with us first — hello@skintique.co.uk.
Frequently Asked Questions
From the Clinic
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Take the skin quizRelated Ingredients
Biotin
A B-complex vitamin that supports skin barrier function and scalp health
Cannabidiol - Derived From Extract Or Tincture Or Resin Of Cannabis
A cannabinoid extract with antioxidant and skin-calming properties
Cannabidiol - Synthetically Produced
A non-psychotropic cannabinoid with potential antioxidant and soothing properties
Cannabis Sativa Flower … Stem Extract
Plant extract with antioxidant and skin-conditioning properties
Cardiospermum Halicacabum Seed Extract
A plant extract traditionally used to address scalp and skin irritation concerns
Cinnamomum Cassia Bark Oil
A warming essential oil with purifying and antioxidant properties from cinnamon bark
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