Skin Conditioning

Cannabis Sativa Callus Lysate

INCI: CANNABIS SATIVA CALLUS LYSATE

Reviewed by Daisy · Last updated 2 Jun 2026

Plant cell extract that conditions and supports skin's natural resilience

Best For Skin Types

All, Dry, Sensitive

Addresses

Dryness, Sensitivity, Barrier repair

Usage Frequency

Daily

What Is Cannabis Sativa Callus Lysate?

Cannabis sativa callus lysate is derived from plant cell cultures (callus tissue) of the cannabis sativa plant. Through a lysing process, the cell contents are released to create a concentrated extract rich in proteins, amino acids, and plant-derived compounds. Unlike cannabis oil or full-plant extracts, this is a controlled cell culture product designed for cosmetic use.

In skincare formulations, it functions primarily as a skin conditioner, helping to improve the texture, hydration and overall feel of the skin.

How It Works

The lysate contains amino acids and proteins that can hydrate the outer layers of skin and help retain moisture. These compounds may also support the skin's natural protective barrier function. Additionally, plant-derived antioxidants present in the extract can help neutralise free radicals that contribute to skin damage and irritation.

The exact mechanism of action varies depending on the specific compounds present and their concentration, which can differ between products.

Clinical Evidence & References

Research on cannabis sativa callus lysate specifically is limited. Most available data comes from ingredient suppliers and formulators rather than independent clinical trials. The ingredient is relatively new to mainstream skincare, so peer-reviewed evidence on efficacy in human skin remains scarce.

General research on cannabis plant extracts suggests antioxidant and anti-inflammatory potential, but specific claims about the callus lysate form require more rigorous testing. If you're considering products containing this ingredient, focus on broader formulation benefits and your own skin's response rather than expecting dramatic results from this component alone.

How to Use

Cannabis sativa callus lysate is typically found in serums, moisturisers and conditioning masks. Use as directed by the product instructions. As with any new skincare ingredient, introduce it gradually into your routine to monitor how your skin responds. It works well alongside other hydrating and antioxidant ingredients.

Safety & Precautions

Generally well-tolerated in cosmetic formulations. No significant cautions reported, though those with known sensitivity to plant extracts should patch test first.

Frequently Asked Questions

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