Peptides

Chlorella Vulgaris Sh-Polypeptide-14

INCI: CHLORELLA VULGARIS SH-POLYPEPTIDE-14

Reviewed by Emma · Last updated 2 Jun 2026

Also known as: Chlorella Vulgaris Sh-polypeptide-14

A green algae extract with antioxidant and skin-conditioning properties

Best For Skin Types

All, Sensitive, Combination

Addresses

Sensitivity, Redness, Barrier repair, Antioxidant protection

Usage Frequency

Daily

What Is Chlorella Vulgaris Sh-Polypeptide-14?

Chlorella vulgaris sh-polypeptide-14 is a peptide derived from chlorella vulgaris, a nutrient-dense freshwater green algae. It is processed to extract bioactive compounds including polysaccharides, polyphenols, and chlorophyll, which are then stabilised in a peptide form for use in skincare formulations.

In cosmetics, this ingredient functions primarily as a skin conditioner and antioxidant, helping to support the skin's natural defences against environmental stressors. It also has antimicrobial properties, making it relevant for formulations targeting sensitivity or reactive skin.

Benefits for Your Skin

How It Works

The peptide components are small enough to penetrate the outer layers of skin, where they deliver the algae's bioactive compounds. These compounds work primarily through antioxidant mechanisms, neutralising reactive oxygen species that contribute to skin ageing and inflammation.

The polysaccharides and polyphenols within the extract also interact with the skin barrier, helping to support hydration and reduce transepidermal water loss. This combination of mechanisms makes it particularly relevant for compromised or sensitive skin conditions.

Clinical Evidence & References

Research on chlorella vulgaris suggests potential benefits in managing inflammatory skin conditions. Animal studies have shown that oral chlorella supplementation can reduce atopic dermatitis-like symptoms, including dermatitis scores and epidermal thickness, though human clinical data remains limited.

Marine microalgae ingredients more broadly have been identified in approximately 27% of sensitive skin formulations from major brands, reflecting industry confidence in their soothing and antioxidant properties. However, specific clinical evidence for the sh-polypeptide-14 form in topical applications is not extensively documented, and further human studies would strengthen the evidence base.

How to Use

This ingredient is typically incorporated into serums, moisturisers, and targeted treatments for sensitive or reactive skin. It works well alongside other skin-conditioning and antioxidant ingredients but does not require special handling or timing. Use as directed within your chosen product formulation.

Safety & Precautions

Chlorella vulgaris derivatives are generally well-tolerated and suitable for most skin types, including sensitive skin. As with any new ingredient, patch test first if you have known sensitivities to algae-derived products.

Frequently Asked Questions

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