Peptides

Capsaicinyl Succinoyl Tripeptide-1

INCI: CAPSAICINYL SUCCINOYL TRIPEPTIDE-1

Reviewed by Rosie · Last updated 2 Jun 2026

Also known as: Capsaicinyl Succinoyl Tripeptide-1

A peptide-based antioxidant designed to protect skin from environmental stress

Best For Skin Types

All, Sensitive, Mature

Addresses

Sensitivity, Redness

Usage Frequency

Daily

What Is Capsaicinyl Succinoyl Tripeptide-1?

Capsaicinyl Succinoyl Tripeptide-1 is a synthetic peptide that combines a tripeptide structure with capsaicin-derived and succinoyl chemistry. Peptides are short chains of amino acids that can penetrate the skin's outer layers and communicate with cells to support various skin functions.

In skincare formulations, this ingredient serves primarily as an antioxidant and skin protectant. It works to neutralise free radicals generated by environmental factors such as UV exposure and pollution, whilst also helping to reinforce the skin's natural defences.

Benefits for Your Skin

How It Works

The ingredient functions as a free radical scavenger, meaning it donates electrons to unstable free radicals and renders them harmless. This prevents oxidative damage to skin cells and collagen.

Additionally, the peptide structure allows the ingredient to interact with skin cells in ways that may strengthen natural protective mechanisms. The specific capsaicin and succinoyl components are designed to enhance these protective and stabilising properties at the cellular level.

Clinical Evidence & References

Evidence specific to Capsaicinyl Succinoyl Tripeptide-1 in published peer-reviewed studies is limited. Much of what is known comes from ingredient manufacturer data and in vitro laboratory studies demonstrating antioxidant activity.

Peptides as a class have established antioxidant and protective properties in skincare, though the efficacy of individual peptides can vary. Anyone seeking visible results should consider this ingredient as part of a broader antioxidant skincare routine rather than as a standalone solution.

How to Use

This ingredient is typically found in serums, moisturisers, and targeted treatment products. Use it as part of your daily routine, ideally in the morning to provide antioxidant defence against daytime environmental exposure, or in the evening as part of your repair regimen. It works well alongside other antioxidants such as vitamin C or niacinamide, and is generally compatible with most skincare ingredients.

Safety & Precautions

Capsaicinyl Succinoyl Tripeptide-1 is generally well-tolerated across skin types. Those with very sensitive skin or known sensitivities to peptides should patch-test before full application.

Frequently Asked Questions

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