Peptides

Capryloyl Dipeptide-17

INCI: CAPRYLOYL DIPEPTIDE-17

Reviewed by Emma · Last updated 2 Jun 2026

Also known as: Capryloyl Dipeptide-17

A peptide-derived conditioning agent that supports skin and hair barrier function

Best For Skin Types

All, Dry, Sensitive, Combination

Addresses

Dryness, Hydration, Barrier repair

Usage Frequency

Daily

What Is Capryloyl Dipeptide-17?

Capryloyl Dipeptide-17 is a synthetic peptide—a short chain of amino acids—combined with caprylic acid, a naturally occurring fatty acid. It functions primarily as a skin and hair conditioning agent, working to improve texture and support the skin's protective barrier.

This ingredient belongs to a broader category of peptide-based cosmetic actives that have gained attention in skincare formulation. Its inclusion in products reflects the growing interest in peptides as multifunctional conditioning agents.

How It Works

Capryloyl Dipeptide-17 works as a humectant and emollient. The peptide component allows it to interact with skin proteins, whilst the fatty acid portion helps trap moisture and create a protective layer on the skin's surface.

Its conditioning effect is thought to stem from its ability to improve how water is distributed within the outer layers of skin, contributing to a smoother appearance and reduced transepidermal water loss.

Clinical Evidence & References

Published research on Capryloyl Dipeptide-17 specifically is limited. Most evidence for peptide-based conditioning agents comes from broader studies on peptides in skincare, which generally support their role in improving skin hydration and texture.

The ingredient appears in safety assessments for cosmetic use, though specific efficacy studies in human subjects are sparse. Like many conditioning agents, its benefits are likely most apparent in formulations designed to support barrier function and hydration rather than address specific skin concerns like acne or hyperpigmentation.

How to Use

This ingredient works best when used as part of a complete skincare routine. Since it functions as a conditioning and hydrating agent, it pairs well with other humectants and emollients. Apply to clean skin, either in serums, moisturisers, or leave-on treatments, and allow time for absorption before applying other products.

Safety & Precautions

Capryloyl Dipeptide-17 is generally well-tolerated in cosmetic formulations. As with any ingredient, patch testing is advisable for those with sensitive skin or known peptide sensitivity.

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