Peptides

Cocoyl Tripeptide-36

INCI: COCOYL TRIPEPTIDE-36

Reviewed by Kate · Last updated 2 Jun 2026

Also known as: Cocoyl Tripeptide-36

A peptide derived from coconut that conditions and supports skin's natural moisture balance

Best For Skin Types

All, Dry, Sensitive, Combination

Addresses

Dryness, Sensitivity, Hydration

Usage Frequency

Daily

What Is Cocoyl Tripeptide-36?

Cocoyl Tripeptide-36 is a peptide—a short chain of amino acids—created by combining coconut-derived fatty acids with three amino acids. Peptides are recognised in skincare for their ability to communicate with skin cells and support structural integrity.

This ingredient functions primarily as a skin conditioning agent, working to improve skin feel, texture, and hydration levels. It is typically included in formulations designed to soften, smooth, and maintain the skin's moisture content.

How It Works

Peptides work by interacting with skin cells to signal maintenance and repair functions. Cocoyl Tripeptide-36, being derived from coconut fatty acids and amino acids, is designed to penetrate or sit on the skin surface to condition and hydrate.

The peptide structure allows it to be smaller and more readily accepted by skin compared to larger proteins, whilst the coconut derivation provides emollient properties that help lock in moisture and improve skin feel.

Clinical Evidence & References

Research on similar coconut-derived peptides and amino acid-based ingredients shows they are well-tolerated and effective in cleansing and conditioning formulations. Studies on related coconut-derived surfactants and amino acid complexes demonstrate their ability to remove impurities whilst preserving skin barrier function and hydration across diverse skin types.

Direct clinical data specific to Cocoyl Tripeptide-36 is limited in publicly available literature. The ingredient's safety profile aligns with broader evidence on acyl amino acid derivatives, which are considered safe for cosmetic use. Further independent research would strengthen the evidence base for this specific peptide.

How to Use

Cocoyl Tripeptide-36 is typically found in cleansers, conditioning treatments, and hydrating formulations. Use as directed by the product instructions—often twice daily for cleansers, or as a treatment as needed. It works well as part of a routine and can be layered with other hydrating or active ingredients without known compatibility issues.

Safety & Precautions

Cocoyl Tripeptide-36 is considered safe for cosmetic use and well-tolerated across skin types. Those with coconut sensitivities should patch test first, though peptide derivatives are generally mild.

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