Creatine
INCI: Adenosine Triphosphate
Reviewed by Daisy · Last updated 14 Aug 2026
Also known as: Adenosine Triphosphate
Amino acid found in the human body Serves as a precursor to adenosine triphosphate
EWG Safety Score
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What Is Creatine?
Creatine is an amino acid found in the human body and most types of meat and fish. This ingredient serves as the precursor to adenosine triphosphate, a skin-restoring and soothing agent. Creatine is located mostly in the body’s muscles and in the brain.
Studies have shown that topically applied creatine can improve the appearance of fine lines and wrinkles. Additional studies have demonstrated that topical creatine can boost skin firmness.
This amino acid may be animal-derived or synthetic; ’s Choice Skin care uses the latter. Typical usage levels of this concentrated ingredient in skin and hair care range from 0.5–1.4%. As a naturally occurring amino acid, it is considered safe as used in cosmetics.
Clinical Evidence & References
- Journal of Cosmetic Dermatology, March 2011 and December 2011, pages 15-23 and 273-281
- Journal of Investigative Dermatology, February 2005, pages 443-452
- Journal of the American Academy of Dermatology, March 2005, page 225
- Biochemical and Biophysical Research Communications, January 2002, pages 47–52
Published Research
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Creatine: Cellular energy for skin repair Nutrients, 2019
Frequently Asked Questions
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Creatine is a variant of Adenosine Triphosphate, the form you will most often see on an ingredients list.
Also called ATP Present in all living cells
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